Simplified protocol for evaluating the genotoxic risk of hospital wastewater

Environmental Toxicology
B Jolibois, M Guerbet

Abstract

To evaluate the genotoxicity of hospital wastewater, we drew up a simplified protocol based on two well-known tests: the SOS chromotest and the Ames fluctuation test. Three concentrations of wastewater samples were directly tested without extraction or concentration. By fixing three significance levels in genotoxicity response for each test, we could classify the samples in five categories ranging from nongenotoxic to highly genotoxic. This simplified classification thus constitutes an invaluable help in making the nonscientist public aware of the genotoxic risk of hospital wastewater and can be applied in a screening approach to chemicals in the environment.

References

Jan 1, 1992·Mutation Research·V Mersch-SundermannS Kevekordes
Feb 1, 1991·Mutation Research·V Mersch-SundermannS Mochayedi
Aug 11, 1991·Ecotoxicology and Environmental Safety·R G Stahl
Feb 1, 1987·Mutation Research·J DayanM Chevron
Jan 1, 1985·The Journal of Pharmacy and Pharmacology·M L Richardson, J M Bowron
Jun 1, 1985·Mutation Research·P Quillardet, M Hofnung
May 1, 1983·Mutation Research·D M Maron, B N Ames
Mar 1, 1997·Ecotoxicology and Environmental Safety·T Steger-HartmannA Hartmann
May 7, 1998·Chemosphere·B Halling-SørensenS E Jørgensen
Jan 15, 1999·Archives of Environmental Contamination and Toxicology·A HartmannR M Widmer

❮ Previous
Next ❯

Citations

Jan 31, 2013·Environmental Science and Pollution Research International·Pratibha SharmaM Sogani
Mar 13, 2014·Analytical Sciences : the International Journal of the Japan Society for Analytical Chemistry·Koki HarigayaJun Haginaka

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Archives of Environmental Contamination and Toxicology
B Jolibois, M Guerbet
The Annals of Occupational Hygiene
B Jolibois, M Guerbet
British Journal of Pharmacology
Richard Maurice Walmsley, Nicholas Billinton
© 2021 Meta ULC. All rights reserved