Simplified protocol of cardiac 18F-fluorodeoxyglucose positron emission tomography viability study in normoglycemic patients with known coronary artery disease

Clinical Imaging
Małgorzata KobyleckaLeszek Królicki

Abstract

The purpose was to evaluate quality of 18F-fluorodeoxyglucose positron emission tomography (18F-FDG-PET) myocardial scans and its correlation with background glucose (BG) after simplified 5% intravenous glucose load protocol. An intravenous glucose load protocol was applied in 69 normoglycemic patients with confirmed coronary artery disease. The blood glucose level was measured every 15 min. Eighty-four percent of images were optimal, 8.7% suboptimal, and 7.3% uninterpretable. The quality of 18F-FDG-PET was BG independent and body mass index dependent (P=.0007). Simplified glucose load protocol is a safe and efficient method of preparation for FDG cardiac viability study in patients with normoglycemia.

References

Jul 25, 2008·Nature Clinical Practice. Cardiovascular Medicine·Heinrich Taegtmeyer, Vasken Dilsizian
Oct 11, 2012·Nuclear Medicine Review. Central & Eastern Europe·Małgorzata KobyleckaLeszek Królicki

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