Simplified surgical placement and stabilization methods for intracerebroventricular cannulas in rat lateral ventricles

Lab Animal
David H JhoN J Espat

Abstract

Intracerebroventricular cannulation in rat models is an efficient tool for exploring the effects of substances directly injected into the CNS, bypassing the blood-brain barrier. Techniques for surgically securing the ICV cannula require a balance between ease of application and adequate stability. The authors tested several methods of lateral ventricle cannula stabilization, especially focusing on a comparison of cyanoacrylate gel to cranioplastic cement with an anchoring bone screw.

References

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Citations

Aug 25, 2007·Epilepsy Research·Blair R HespD Steven Kerr
Oct 7, 2014·Journal of Neuroscience Methods·Skyler J Mooney, Melissa M Holmes
Feb 23, 2019·Frontiers in Neuroscience·Parto S Khansari, Robert F Halliwell

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