Abstract
Because of their rarity, outcomes regarding spinal atypical meningiomas (AMs) remain unclear. To describe the recurrence rate and postoperative outcomes after resection of spinal AMs, and to discuss an appropriate resection strategy and adjuvant therapy for spinal AMs. Data from all patients who presented with spinal AMs to 2 tertiary referral centers between 1998 and 2013 were obtained by chart review. From 102 patients with spinal meningioma, 20 AM tumors (7 cervical, 11 thoracic, 2 thoracolumbar) were identified in 18 patients (median age, 50 years [range, 19-75] at time of resection; 11% male; median follow-up, 32 months [range, 1-179] after resection). Before resection, patients had sensory deficits (70%), pain (70%), weakness (60%), ataxia (50%), spasticity (65%), and incontinence (35%). One tumor presented asymptomatically. Simpson grade I, II, III, and IV resection were achieved in 3 (15%), 13 (65%), 2 (10%), and 2 (10%) tumors, respectively. One patient that underwent Simpson grade III resection received adjuvant radiation therapy. After Simpson grade I-III or gross total resection, no tumors recurred (0%; confidence interval, 0%-17.6%). After Simpson grade IV resection, 1 tumor recurred (50%; confidence interval, 1.3%...Continue Reading
References
Apr 1, 1990·Journal of Neurosurgery·P C McCormickB M Stein
Aug 1, 1989·Neurosurgery·C L SoleroF Pluchino
Jan 1, 1985·Journal of Neurosurgery·R O MirimanoffR L Martuza
Dec 1, 1982·Journal of Neurosurgery·W J LevyD Dohn
Jul 1, 1993·Brain Pathology·P KleihuesB W Scheithauer
Nov 1, 1996·Surgical Neurology·F X RouxJ F Meder
Mar 10, 1999·British Journal of Neurosurgery·A T KingJ R Bartlett
Feb 5, 2000·Surgical Neurology·J Klekamp, M Samii
Apr 7, 2000·Spine·F GezenA Bedük
Aug 9, 2001·Spine·T SaitoY Iwamoto
Feb 1, 1957·Journal of Neurology, Neurosurgery, and Psychiatry·D SIMPSON
Sep 30, 2004·Spine·Xavier MorandiGilles Brassier
Jan 27, 2005·Neurosurgical Focus·Oren N GottfriedMeic H Schmidt
Dec 24, 2005·Journal of Neurosurgery. Spine·Patrick CramerChristian Woiciechowsky
Jul 10, 2007·Acta Neuropathologica·David N LouisPaul Kleihues
Oct 27, 2007·Neurosurgical Focus·Matthias SetzerFrank D Vrionis
Dec 29, 2007·Neurosurgery·Burak SadeJoung H Lee
Apr 9, 2008·Journal of Orthopaedic Science : Official Journal of the Japanese Orthopaedic Association·Yoshiharu KawaguchiTomoatsu Kimura
May 2, 2008·Neurosurgical Focus·Blake E PearsonKristen Riley
May 16, 2008·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·I Erol SandalciogluSiamak Asgari
Jan 16, 2009·Neurosurgery·Manish K AghiFred G Barker
Aug 27, 2010·Journal of Neuro-oncology·Leland RogersMichael A Vogelbaum
Oct 12, 2010·Clinical Neurology and Neurosurgery·F MaiuriG Mariniello
Aug 28, 2012·Journal of Neurosurgery·Ricardo J KomotarPhilip H Gutin
Feb 12, 2013·Journal of Neurosurgery·Douglas A HardestyNader Sanai
Mar 27, 2013·Nature Reviews. Neurology·Patricia L ZadnikChetan Bettegowda
Dec 3, 2013·Neurosurgical Focus·Kangmin D LeeChristopher M McPherson
Jun 4, 2014·Neuro-oncology·Ayal A AizerBrian M Alexander
Jun 17, 2014·Neurosurgery·Sam Q SunMichael R Chicoine
Jun 17, 2014·Neurosurgery·Sam Q SunAlbert H Kim
Mar 3, 2015·Neurosurgical Focus·Sam Q SunAlbert H Kim
Citations
Mar 26, 2016·Neurosurgery Clinics of North America·Vijay M Ravindra, Meic H Schmidt
Jun 25, 2016·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Iddo PaldorYigal Shoshan
Aug 2, 2016·Neurosurgical Focus·Tanmoy K MaitiAnil Nanda
Sep 18, 2016·World Neurosurgery·Alvaro Otero-RodriguezLaura Ruiz-Martin
Sep 14, 2018·Journal of Neuro-oncology·Lingyang HuaYe Gong
Mar 9, 2018·Neurosurgical Review·Alessandro FratiAntonino Raco
Dec 14, 2018·Journal of Neurosurgery. Spine·Julia OnkenMaria Wostrack
Feb 13, 2018·Oncology Letters·Shanyong ZhangMinfei Wu
Apr 9, 2016·Journal of Neuro-oncology·Jingliang YeChun Luo
Sep 26, 2020·Frontiers in Oncology·Lianhua ZhaoZaiyu Guo
Nov 26, 2019·World Neurosurgery·Hui ZhangYan Zhou