Simul 5 - free dynamic simulator of electrophoresis

Electrophoresis
Vlastimil HruskaBohuslav Gas

Abstract

We introduce the mathematical model of electromigration of electrolytes in free solution together with free software Simul, version 5, designed for simulation of electrophoresis. The mathematical model is based on principles of mass conservation, acid-base equilibria, and electroneutrality. It accounts for any number of multivalent electrolytes or ampholytes and yields a complete picture about dynamics of electromigration and diffusion in the separation channel. Additionally, the model accounts for the influence of ionic strength on ionic mobilities and electrolyte activities. The typical use of Simul is: inspection of system peaks (zones), stacking and preconcentrating analytes, resonance phenomena, and optimization of separation conditions, in either CZE, ITP, or IEF.

References

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Citations

Mar 20, 2013·Chemical Reviews·Naomi L Kuehnbaum, Philip Britz-McKibbin
Aug 11, 2011·Bioanalysis·David S Wishart
Feb 13, 2014·Analytical Chemistry·Merav KarsentyMoran Bercovici
Jan 22, 2014·Journal of Chromatography. a·Anita RogacsJuan G Santiago
Sep 27, 2014·Lab on a Chip·Tally Rosenfeld, Moran Bercovici
Dec 8, 2009·Journal of Chromatography. a·Ying Chou, Ruey-Jen Yang
Jun 12, 2009·Electrophoresis·Wolfgang ThormannRichard A Mosher
Feb 5, 2008·Electrophoresis·Jia-Wei YuRuey-Jen Yang
Feb 20, 2007·Journal of Separation Science·Jan PetrZdenek Stránský
Apr 3, 2008·Electrophoresis·Wolfgang Thormann, Richard A Mosher
Dec 21, 2006·Electrophoresis·Vlastimil Hruska, Bohuslav Gas
Feb 8, 2008·Electrophoresis·Jaesool ShimCornelius F Ivory
Feb 11, 2011·Electrophoresis·Supreet S BahgaJuan G Santiago
Apr 25, 2012·Electrophoresis·Martina RiesováBohuslav Gaš
Apr 25, 2012·Electrophoresis·Vlastimil HruškaBohuslav Gaš
Jan 23, 2016·Electrophoresis·Jitka CaslavskaWolfgang Thormann
Nov 29, 2013·Electrophoresis·Marko StojkovicPeter C Hauser
Dec 25, 2007·Analytica Chimica Acta·Pavel Kubán, Peter C Hauser
Jun 5, 2015·Electrophoresis·Scott D Noblitt, Charles S Henry

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