Simulated weight reduction using an anti-gravity treadmill - A pilot study of the impact of weight loss on foot and ankle arthritis.

Foot and Ankle Surgery : Official Journal of the European Society of Foot and Ankle Surgeons
William J MorleyRoyal Bournemouth and Christchurch Hospitals NHS Foundation Trust UK

Abstract

Despite a paucity of evidence, obesity is frequently cited as an exacerbator of symptoms in foot and ankle arthritis. The aims of the current study were to determine whether simulated weight loss would improve symptoms in obese patients with foot and ankle arthritis. Patients walked on an "anti-gravity" treadmill allowing simulated weight reduction. Pain was recorded at baseline weight and then compared with pain at simulated normal BMI. Simulated reduction to BMI 25 caused a significant reduction in pain. Mean pain scores improved from baseline to BMI 25 by 32% (15.9 points, p=0.04). Paired analysis showed a significant improvement in pain scores (p=0.016) from BMI of 30 to 25. Simulated weight loss from high to normal BMI improved arthritic symptoms. This could be used to power future studies to further investigate the effects of weight loss in foot and ankle patients. Level of evidence Level II - repeated measures cohort study.

References

Sep 13, 2000·Journal of the American Geriatrics Society·S P MessierW H Ettinger
Jun 30, 2005·Arthritis and Rheumatism·Stephen P MessierPaul DeVita
Oct 14, 2006·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·H Bliddal, R Christensen
Jan 6, 2007·Annals of the Rheumatic Diseases·Robin ChristensenHenning Bliddal
Jun 1, 2012·PM & R : the Journal of Injury, Function, and Rehabilitation·Heather K VincentRobert W Hurley
May 29, 2012·The Journal of Bone and Joint Surgery. American Volume·Sanjeev Sabharwal, Michael Z Root
Sep 19, 2012·Obesity Surgery·Sonia M FabrisIvan Cecconello
Jan 11, 2014·BMC Musculoskeletal Disorders·Mark StegemanBartele Alexander Swierstra
Apr 23, 2014·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·H BliddalR Christensen
Mar 27, 2015·Foot & Ankle International·Gowreeson ThevendranAlastair S E Younger
May 8, 2015·Anaesthesia·UNKNOWN Members of the Working PartyUNKNOWN Ireland Society for Obesity and Bariatric Anaesthesia
Nov 27, 2016·Obesity Research & Clinical Practice·Alyssa B DufourMarian T Hannan
May 22, 2019·The British Journal of General Practice : the Journal of the Royal College of General Practitioners·Rachel FergusonCatherine Bowen

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