DOI: 10.1101/502435Dec 20, 2018Paper

Simulating the Monty Hall problem in a DNA sequencing machine

BioRxiv : the Preprint Server for Biology
Noam MametIdo Bachelet

Abstract

The Monty Hall problem is a decision problem with an answer that is surprisingly counter-intuitive yet provably correct. Here we simulate and prove this decision in a high- throughput DNA sequencing machine, using a simple encoding. All possible scenarios are represented by DNA oligonucleotides, and gameplay decisions are implemented by sequencing these oligonucleotides from specific positions, with a single run simulating more than 12,000,000 independent games. This work highlights high-throughput DNA sequencing as a new tool that could extend existing capabilities and enable new encoding schemes for problems in DNA computing.

Related Concepts

DNA
Oligonucleotides
Decision
Nucleic Acid Sequencing
Human DNA Sequencing
DNA Aptamers
High-Throughput DNA Sequencing

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