Simultaneous analysis of antioxidants and preservatives in cosmetics by supercritical fluid extraction combined with liquid chromatography-mass spectrometry

Journal of Chromatography. a
Maw-Rong LeeTzu-Feng Tsai

Abstract

This study evaluated supercritical fluid extraction (SFE) combined with liquid chromatography-mass spectrometry (LC-MS) to determine trace preservatives and antioxidants including methylparaben (MP), ethylparaben (EP), propylparaben (PP), butylparaben (BP), butylated hydroxyanisole (BHA), butylated hydroxytoluene (BHT), alpha-tocopherol (alpha-t) and alpha-tocopherol acetate (alpha-ta) in cosmetic products. A supercritical fluid extraction procedure was used to isolate four paraben preservatives and four antioxidants from the cosmetic matrix before quantitative analysis. The optimum extraction condition was performed with static extraction for 5 min, then dynamic extraction for 20 min by using carbon dioxide supercritical fluid at 14,000 kPa and 65 degrees C. Methanol was used as collection solvent and the sea sand was chosen as a filling material. The analytes were separated on a C18 reversed-phase column using methanol-water as mobile phase and quantified by measuring its mass spectrometry. The linearity range is from 10 to 20,000 ng/g with RSD values below 18%. Detection limits are achieved at the level of 4.7-142 ng/g. It was successfully applied to the determination of paraben preservatives and antioxidants in cosmetics wi...Continue Reading

References

Jul 10, 1999·Journal of Chromatography. a·G R van der Hoff, P van Zoonen
Nov 7, 2002·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·S Oishi
Apr 19, 2005·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·M G SoniG A Burdock

❮ Previous
Next ❯

Citations

Jul 16, 2011·International Journal of Analytical Chemistry·Mohammed AkkbikFasihuddin Badruddin Ahmad
Aug 3, 2014·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·José Manuel Pérez MartínMaría José Hazen
Jan 20, 2015·Analytica Chimica Acta·Juan Antonio Ocaña-GonzálezMiguel Angel Bello-López
May 9, 2013·International Journal of Cosmetic Science·D N de OliveiraR Catharino
Apr 8, 2016·Journal of Pharmaceutical and Biomedical Analysis·Raffaele LecceAlessia Panusa
Jan 27, 2015·Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment·Juan Ignacio CachoManuel Hernández-Córdoba
May 24, 2016·Bioanalysis·Shirish YakkundiJames McElnay
Jan 18, 2013·Journal of Chromatographic Science·Irena BaranowskaEwa Krutysza
Oct 19, 2016·Chemical Communications : Chem Comm·Anilkumar GunnamAshwini Nangia
May 22, 2010·Journal of Separation Science·Lidervan P Melo, Maria Eugênia C Queiroz
Sep 29, 2011·Analytical and Bioanalytical Chemistry·Lucia Sanchez-PradoMaria Llompart
Jan 20, 2012·Biofouling·Lindsey A LorenzDavid R Macinga
Jun 16, 2018·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Geaneth Pertunia MashilePhiliswa Nosizo Nomngongo
Feb 28, 2007·Journal of Mass Spectrometry : JMS
Aug 28, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Pascaline Aimee Uwineza, Agnieszka Waśkiewicz
May 25, 2007·Chemical Reviews·Lawrence H KeithJennifer L Young

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.