Simultaneous analysis of wall motion and coronary flow reserve of the left anterior descending coronary artery by transthoracic doppler echocardiography during dipyridamole stress echocardiography

Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography
Jorge LowensteinCristina Quiroz

Abstract

Coronary flow reserve (CFR) can be measured in the left anterior descending artery (LAD) by dipyridamole transthoracic Doppler echocardiography (DTTDE). This information may critically improve the diagnostic accuracy of dipyridamole stress echocardiography, which is limited by moderate sensitivity. We sought to assess the feasibility and accuracy of value of DTTDE. We evaluated 752 consecutive patients (478 men; mean age, 64.7 years) referred for dipyridamole stress echocardiography. The diastolic velocity in the LAD was continuously monitored with pulsed Doppler at baseline and during hyperemia induced by the infusion of 0.84 mg/kg of dipyridamole. CFR was calculated as the ratio of maximal and basal diastolic velocity; a value < 2 was considered to indicate decreased CFR. Wall motion was assessed semiquantitatively. Coronary angiography was performed in 132 patients the week after DTTDE. Adequate tracings were obtained in 95% of patients studied (715 of 752). In the subset of 132 patients undergoing coronary angiography, 71 patients (group A) showed a nonsignificant (<70%) and 61 patients (group B) a significant stenosis of the LAD. In group A, 65 had a normal wall-motion response (91.5% specificity) and 19 patients showed a ...Continue Reading

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Citations

Dec 4, 2009·European Journal of Nuclear Medicine and Molecular Imaging·Cecilia MariniGianmario Sambuceti
Jul 15, 2005·The International Journal of Cardiovascular Imaging·Eugenio Picano
Jul 6, 2014·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Jorge A LowensteinVictor Darú
Oct 19, 2010·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Nicola GaibazziClaudio Reverberi
Feb 23, 2010·Heart, Lung & Circulation·Thomas H Marwick
Apr 3, 2007·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Wendy S TzouJames H Stein
Aug 2, 2006·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Tsutomu TakagiJunichi Yoshikawa
Jun 29, 2004·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Fausto RigoEugenio Picano
Dec 31, 2003·The American Journal of Cardiology·Fabio ChirilloPaolo Stritoni
Feb 26, 2008·European Journal of Echocardiography : the Journal of the Working Group on Echocardiography of the European Society of Cardiology·Patrick Meimoun, Christophe Tribouilloy
Mar 25, 2004·Expert Review of Cardiovascular Therapy·Eugenio Picano
Jun 28, 2006·Journal of Cardiovascular Medicine·Fausto RigoLauro Cortigiani
Aug 10, 2016·European Heart Journal Cardiovascular Imaging·Angela Zagatina, Nadezhda Zhuravskaya
May 31, 2020·Cardiovascular Ultrasound·Marloes SjoerdsmaRichard Gp Lopata
Oct 4, 2020·Journal of Clinical Medicine·Eugenio PicanoQuirino Ciampi
Jul 10, 2021·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Fang-Shin LiuYen-Wen Wu

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