Simultaneous covalent and noncovalent hybrid polymerizations

Science
Zhilin YuSamuel I Stupp

Abstract

Covalent and supramolecular polymers are two distinct forms of soft matter, composed of long chains of covalently and noncovalently linked structural units, respectively. We report a hybrid system formed by simultaneous covalent and supramolecular polymerizations of monomers. The process yields cylindrical fibers of uniform diameter that contain covalent and supramolecular compartments, a morphology not observed when the two polymers are formed independently. The covalent polymer has a rigid aromatic imine backbone with helicoidal conformation, and its alkylated peptide side chains are structurally identical to the monomer molecules of supramolecular polymers. In the hybrid system, covalent chains grow to higher average molar mass relative to chains formed via the same polymerization in the absence of a supramolecular compartment. The supramolecular compartments can be reversibly removed and re-formed to reconstitute the hybrid structure, suggesting soft materials with novel delivery or repair functions.

References

Apr 18, 1997·Science·S I StuppA Amstutz
Jan 29, 2000·Angewandte Chemie·R B PrinceJ S Moore
Nov 27, 2001·Science·J D HartgerinkS I Stupp
Dec 13, 2001·Chemical Reviews·D J HillJ S Moore
Mar 29, 2003·Physiological Reviews·C G dos RemediosN J Nosworthy
Dec 25, 2003·Journal of the American Chemical Society·Dahui Zhao, Jeffrey S Moore
Jan 18, 2006·Accounts of Chemical Research·Matthew T StoneJeffrey S Moore
Jan 1, 1993·Science·S I StuppL S Li
Mar 5, 2008·Journal of the American Chemical Society·Lorraine HsuSamuel I Stupp
Dec 3, 2008·The Journal of Chemical Physics·Claire L PizzeyNicholas L Abbott
Feb 6, 2009·Nano Letters·Honggang CuiSamuel I Stupp
Mar 20, 2010·Science·Jacqui M A CarnallSijbren Otto
Nov 26, 2010·Nature Chemistry·Andrew R HirstRein V Ulijn
Nov 30, 2010·Chemical Society Reviews·Jean-Baptiste Guilbaud, Alberto Saiani
Feb 24, 2011·Journal of the American Chemical Society·One-Sun LeeGeorge C Schatz
Apr 13, 2011·Chemical Communications : Chem Comm·Gilles Guichard, Ivan Huc
Feb 22, 2012·Science·T AidaS I Stupp
May 19, 2012·Chemical Reviews·Dingcai WuKrzysztof Matyjaszewski
Jan 24, 2014·Nature Chemistry·Jiyeong LeeKimoon Kim
Feb 28, 2014·Journal of the American Chemical Society·Tao JiangVincent P Conticello
Apr 30, 1998·The Journal of Physical Chemistry. B·A D MacKerellM Karplus

❮ Previous
Next ❯

Citations

Apr 15, 2016·Macromolecular Rapid Communications·Linyi Bai, Yanli Zhao
Apr 19, 2016·Chemical Communications : Chem Comm·Zhaoqianqi FengBing Xu
Jun 25, 2016·Chemistry : a European Journal·Xisen HouJ Fraser Stoddart
Nov 1, 2016·Nano Letters·Zhilin YuSamuel I Stupp
Jan 31, 2017·Journal of the American Chemical Society·Jinlian CaoYun-Bao Jiang
May 10, 2017·Angewandte Chemie·Huaimin WangBing Xu
Mar 13, 2020·Advanced Materials·Oliver DumeleSamuel I Stupp
Mar 30, 2019·Science·Ghislaine Vantomme, E W Meijer
Jul 28, 2016·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Yan-Jun LiuMing-Guo Ma
May 10, 2020·Nature Communications·Krishnachary SalikolimiYasuhiro Ishida
Aug 3, 2017·Nanoscale·Xuejiao YangZhimin He
Mar 8, 2019·Nature Communications·Bowen ShenMyongsoo Lee
Jun 19, 2020·International Journal of Molecular Sciences·Raffaele Pugliese, Fabrizio Gelain
Jun 24, 2020·Nature Materials·Chuang LiSamuel I Stupp
Apr 27, 2016·Chemical Communications : Chem Comm·Xin WuYun-Bao Jiang
Mar 30, 2016·Chemical Communications : Chem Comm·Zhilin Yu, Stefan Hecht
Jun 24, 2017·Nature Chemistry·Ryan BaumgartnerJianjun Cheng
Oct 25, 2017·Nature Chemistry·Urszula LewandowskaHelma Wennemers
Oct 18, 2020·International Journal of Molecular Sciences·Noriyuki Uchida, Takahiro Muraoka
Dec 9, 2020·Nature Communications·Joonsik SeoJong-Man Kim
Jan 14, 2021·Chemical Society Reviews·George T WilliamsPhilip A Gale
Nov 29, 2020·Angewandte Chemie·Guillermo Moreno-AlcántarLuisa De Cola
Oct 22, 2020·Progress in Polymer Science·Tristan D Clemons, Samuel I Stupp

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2021 Meta ULC. All rights reserved