Simultaneous development of Kaposi's sarcoma and lymphoma in a renal transplant recipient

American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation
A SabeelK al-Meshari

Abstract

Kaposi's sarcoma (KS) and non-Hodgkin's lymphoma are frequent complications of renal transplantation that usually occur as separate entities. We describe a young woman who simultaneously developed Kaposi's sarcoma and lymphoma after kidney transplantation. Immunosuppression consisted of cyclosporine and prednisone with normal serum creatinine. Fifteen months after transplantation, she developed Kaposi's sarcoma skin lesions, generalized lymphadenopathy, and ascites. A lymph node biopsy showed both Kaposi's sarcoma and lymphoma in the same tissue specimen with Epstein-Barr viral genomes within the tumor cells. Graft function remained normal. Cyclosporine was discontinued, and treatment with acyclovir was started, but the patient's condition rapidly deteriorated, and she died. This is the first case in which both Kaposi's sarcoma and lymphoma were present in the same biopsy specimen. After renal transplantation, more than one tumor can develop either simultaneously or in succession.

Citations

Apr 25, 2012·Asian Pacific Journal of Cancer Prevention : APJCP·Mahira YunusMuhammed Mubarak
Nov 3, 2005·Clinics in Chest Medicine·Leanne B Gasink, Emily A Blumberg
Jul 29, 2008·Transplantation Reviews·Céleste LebbéCamille Francès
Sep 15, 1998·The American Journal of Pathology·K E ForemanB J Nickoloff
Jun 11, 2009·Transplant Infectious Disease : an Official Journal of the Transplantation Society·L McPheeJ P Vella
Jul 26, 2000·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·G GüzM Haberal
Aug 8, 2009·International Journal of Surgical Pathology·Aashiyana F KoreishiJulie Teruya-Feldstein

❮ Previous
Next ❯

Related Concepts

Related Feeds

Blood And Marrow Transplantation

The use of hematopoietic stem cell transplantation or blood and marrow transplantation (bmt) is on the increase worldwide. BMT is used to replace damaged or destroyed bone marrow with healthy bone marrow stem cells. Here is the latest research on bone and marrow transplantation.

B-Cell Lymphoma

B-cell lymphomas include lymphomas that affect B cells. This subtype of cancer accounts for over 80% of non-Hodgkin lymphomas in the US. Here is the latest research.

© 2022 Meta ULC. All rights reserved