Simultaneous Doppler tracing of the mitral inflow and annular motion provides a useful means of evaluating left ventricular diastolic function.

Clinical Cardiology
Jin-Oh ChoiSang-Chol Lee

Abstract

In this study, we evaluated the feasibility and clinical usefulness of TS(E-E(') ), the time interval between the onsets of early diastolic mitral inflow velocity (E) and mitral annular velocity (E'), obtained by simultaneously tracing E and E', in terms of evaluating diastolic function. By the diastolic functional status, 105 patients were allocated to abnormal relaxation, pseudonormal filling (PN), or normal diastolic function groups (n = 30, 43, and 32, respectively). The TS(E-E(') ) was measured in the same cardiac cycle by the pulsed-wave Doppler (PWD) tracing of mitral inflow near the septal annulus with appropriate filter and gain settings. TS(E-E(') ) was prolonged in the PN group versus the normal group (34.1 +/- 12.2 msec versus 12.1 +/- 8.5 msec, p< or =0.001). The area under the receiver operating characteristic curve of TS(E-E(') ) for the detection of PN was 0.91 (95% confidence interval [CI]; 0.85 approximately 0.97, p<0.001), and 24.0 msec was determined to be the optimal cut-off value (specificity 83.7%, sensitivity 90.3%). Simultaneous measurement of TS(E-E(') ) is feasible and clinically applicable for the grading of diastolic dysfunction (DD).

References

Jan 9, 2003·JAMA : the Journal of the American Medical Association·Margaret M RedfieldRichard J Rodeheffer
Mar 26, 2003·Journal of the American College of Cardiology·Allison M PritchettMargaret M Redfield
Apr 16, 2003·Circulation·Jacob E MollerPatricia A Pellikka
Oct 18, 2003·Journal of the American College of Cardiology·Jae K Oh, Jamil Tajik
Nov 13, 2003·European Journal of Echocardiography : the Journal of the Working Group on Echocardiography of the European Society of Cardiology·A StoylenS Slørdahl
Feb 26, 2004·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Samer J KhouriThomas E Walsh
Jan 5, 2005·Journal of the American College of Cardiology·Allison M PritchettMargaret M Redfield
Feb 6, 2007·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Gregory GilmanSteve R Ommen

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Citations

Jan 5, 2012·Circulation Journal : Official Journal of the Japanese Circulation Society·Yasuaki WadaMasunori Matsuzaki

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