Simultaneous Gastric Metastasis From Renal Cell Carcinoma: A Case Report and Literature Review

Clinical Medicine Insights. Case Reports
Noriyuki ArakawaHiroshi Hojo

Abstract

While some reports are available regarding metachronous gastric metastasis from renal cell carcinoma after treatment, there are few reports of primary lesion detection based on the diagnosis of a gastric metastatic lesion. The patient in this case was an 80-year-old woman who underwent upper gastrointestinal endoscopy after having developed anorexia 2 months earlier. A submucosal tumor with central umbilication was found in the gastric greater curvature. Endoscopic ultrasonography revealed a solid and hypoechoic mass with hypervascularity on color Doppler imaging that proliferated mainly within the submucosal layer. There was partial exposure of the tumor on the superficial layer. Biopsy was performed, as a neuroendocrine tumor was suspected; however, histopathological findings with immunostaining revealed gastric metastasis from clear renal cell carcinoma. Subsequently, contrast enhanced computed tomography showed right renal cell carcinoma and liver metastasis. Thus, molecularly targeted drug treatment was initiated by the Department of Urology. Our findings indicate that a primary lesion can be identified and prognosis can be assumed based on biopsy of the gastric metastatic lesion. Immunostaining of biopsy samples collected...Continue Reading

References

Apr 1, 1980·Urology·W G SullivanR E Donohue
Mar 14, 2008·BJU International·Marion J PollheimerCord Langner
Nov 6, 2009·Gastric Cancer : Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association·Daigo YamamotoMitsuo Yamamoto
Oct 29, 2010·Urology Annals·Punit TiwariA K Kundu
Sep 20, 2012·International Journal of Surgery Case Reports·Jie XuShi Wei
Apr 1, 2014·Clinical Journal of Gastroenterology·Herculano RitaMatos Leopoldo

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Citations

Jan 12, 2021·IJU Case Reports·Shigeki KoterazawaShouichi Fukui
Apr 12, 2021·International Journal of Surgery Case Reports·Thomas PrudhommeFabrice Muscari

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Methods Mentioned

BETA
biopsy

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