Simultaneous indocyanine green and (99m)Tc-antimony sulfur colloid-guided laparoscopic sentinel basin dissection for gastric cancer

Annals of Surgical Oncology
Do Joong ParkHan-Kwang Yang

Abstract

There are few reports on a dual dye and isotope approach using laparoscopy in gastric cancer sentinel node mapping. The aim of this study is to evaluate the feasibility of laparoscopic sentinel basin dissection for gastric cancer using simultaneous indocyanine green (ICG) and (99m)Tc-antimony sulfur colloid (ASC) injections. Sixty-eight patients were enrolled who had been diagnosed with cT1-T2 and cN0 stage gastric cancers. They underwent laparoscopic sentinel basin dissection between June 2005 and May 2008. ICG and (99m)Tc-tin colloid (separate injections in the first phase, n = 16) or ICG and (99m)Tc-ASC (simultaneous injections in the second phase, n = 52) were injected into the submucosa endoscopically. After performing the sentinel basin dissection, laparoscopy-assisted gastrectomy with curative lymphadenectomy was done. Green-stained or radioactive sentinel nodes (SNs) were analyzed by hematoxylin and eosin staining and by immunohistochemistry for cytokeratin. SNs were identified in 62 of the 68 patients (91.2%; mean 3.3 per patient). Eighteen patients had lymph node metastases. The sensitivity and specificity were, respectively, 72.2 and 100% using the dye method and 83.3 and 100% by the isotope method. However, the dual...Continue Reading

References

Sep 1, 1994·Annals of Surgery·A E GiulianoD L Morton
Mar 7, 2001·Surgery·M HiratsukaH Koyama
Apr 17, 2002·Gastric Cancer : Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association·Jin-Pok KimHan-Kwang Yang
Apr 26, 2002·The British Journal of Surgery·Y KitagawaM Kitajima
Oct 16, 2002·Gastric Cancer : Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association·Hyuk-Joon LeeYoon-Ok Ahn
Jan 9, 2003·Journal of the American College of Surgeons·Hideki HayashiHideaki Shimada
Jan 30, 2003·The British Journal of Surgery·K MiwaA Nonomura
Aug 9, 2003·The New England Journal of Medicine·Umberto VeronesiRoberto Gennari
Apr 13, 2004·Annals of Surgery·Min-Chan KimJin-Sook Jeong
Nov 5, 2005·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·D J ParkH-K Yang
Jan 2, 2007·Annals of Surgery·Seigo KitanoUNKNOWN Japanese Laparoscopic Surgery Study Group
Dec 25, 2008·Annals of Surgery·Yusuke TajimaMitsuo Kusano

❮ Previous
Next ❯

Citations

Feb 1, 2014·Gastric Cancer : Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association·Seong-Ho KongHan-Kwang Yang
Jun 13, 2013·Journal of Laparoendoscopic & Advanced Surgical Techniques. Part a·Mehmet Fatih CanSadettin Cetiner
Dec 20, 2015·Current Problems in Surgery·Dan E AzaguryBrendan C Visser
Dec 22, 2017·Plastic and Reconstructive Surgery. Global Open·Andrew McGregorDeepak Narayan
Nov 9, 2011·Journal of the Korean Surgical Society·Hyung-Ho Kim, Sang-Hoon Ahn
Apr 14, 2012·Journal of Gastric Cancer·Young-Woo KimJi Yeon Park
Mar 1, 2019·Journal of Gastrointestinal Cancer·Georgios D LianosStefano Rausei
Nov 28, 2013·Annals of Surgical Oncology·Ju-Hee LeeHan-Kwang Yang
Nov 4, 2011·Annals of Surgical Oncology·Zhen WangJin-Lu Liu
Oct 14, 2011·Current Opinion in Gastroenterology·Abdulzahra Hussain
May 7, 2013·World Journal of Surgery·Alessandra MaranoGiuseppe Spinoglio
Apr 18, 2017·Journal of Clinical Nursing·Hee-Young Kim, Kyung-Sook Bang
Jul 19, 2012·Journal of Surgical Oncology·Han-Kwang YangHyuk-Joon Lee
Sep 26, 2019·Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen·Andrea PicchettoMichele Diana
Oct 24, 2014·World Journal of Gastroenterology : WJG·Sang-Yong Son, Hyung-Ho Kim
Apr 18, 2012·Journal of Gastroenterology and Hepatology·Masashi YoshidaMasaki Kitajima
Jul 6, 2019·Gastric Cancer : Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association·Gijsbert I van BoxelRichard van Hillegersberg

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.