Simultaneous measurement of noise and spatial resolution in PET phantom images.

Physics in Medicine and Biology
Martin A LodgeRichard L Wahl

Abstract

As an aid to evaluating image reconstruction and correction algorithms in positron emission tomography, a phantom procedure has been developed that simultaneously measures image noise and spatial resolution. A commercially available (68)Ge cylinder phantom (20 cm diameter) was positioned in the center of the field-of-view and two identical emission scans were sequentially performed. Image noise was measured by determining the difference between corresponding pixels in the two images and by calculating the standard deviation of these difference data. Spatial resolution was analyzed using a Fourier technique to measure the extent of the blurring at the edge of the phantom images. This paper addresses the noise aspects of the technique as the spatial resolution measurement has been described elsewhere. The noise measurement was validated by comparison with data obtained from multiple replicate images over a range of noise levels. In addition, we illustrate how simultaneous measurement of noise and resolution can be used to evaluate two different corrections for random coincidence events: delayed event subtraction and singles-based randoms correction. For a fixed number of iterations of the maximum-likelihood expectation-maximizati...Continue Reading

References

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Jul 21, 2009·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Martin A LodgeRichard L Wahl

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Citations

Jul 8, 2014·Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)·Masashi YagiSusanta K Hui
Mar 21, 2015·Acta Radiologica Open·Jan H GeismarLars Husmann
Jan 23, 2014·Critical Care Medicine·João Batista BorgesGöran Hedenstierna
Jan 10, 2018·Computational and Mathematical Methods in Medicine·Marco D'Arienzo, Maurice Cox
Sep 14, 2013·Physics in Medicine and Biology·Arman Rahmim, Jing Tang
Apr 26, 2019·Journal of Nuclear Medicine Technology·Frank P DiFilippoSagar Patel
Jun 16, 2018·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Martin A LodgeEric C Frey

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