Simultaneous Multi-plane Imaging of Neural Circuits

Neuron
Weijian YangDarcy S Peterka

Abstract

Recording the activity of large populations of neurons is an important step toward understanding the emergent function of neural circuits. Here we present a simple holographic method to simultaneously perform two-photon calcium imaging of neuronal populations across multiple areas and layers of mouse cortex in vivo. We use prior knowledge of neuronal locations, activity sparsity, and a constrained nonnegative matrix factorization algorithm to extract signals from neurons imaged simultaneously and located in different focal planes or fields of view. Our laser multiplexing approach is simple and fast, and could be used as a general method to image the activity of neural circuits in three dimensions across multiple areas in the brain.

References

Apr 6, 1990·Science·W DenkW W Webb
Jan 1, 1997·Spatial Vision·D H Brainard
Jul 7, 2000·Journal of the Optical Society of America. A, Optics, Image Science, and Vision·A Egner, S W Hell
Oct 2, 2001·Current Opinion in Chemical Biology·R M WilliamsW W Webb
Sep 5, 2002·Applied Optics·Emmanuel Beaurepaire, Jerome Mertz
Nov 5, 2003·Nature Biotechnology·Warren R ZipfelWatt W Webb
Jun 3, 2005·Applied Optics·Matthias Fricke, Tim Nielsen
Jul 22, 2005·Annual Review of Neuroscience·Michael London, Michael Häusser
Nov 22, 2005·Nature Methods·Fritjof Helmchen, Winfried Denk
Nov 23, 2007·Optics Letters·V AndresenS W Hell
Dec 19, 2007·Optics Letters·J BewersdorfS W Hell
Feb 13, 2008·IEEE Transactions on Image Processing : a Publication of the IEEE Signal Processing Society·P ThévenazM Unser
Apr 25, 2008·Nature Neuroscience·Gaddum Duemani ReddyPeter Saggau
Jul 9, 2008·Optics Express·Ramón CarrilesVirginijus Barzda
Jul 25, 2008·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Cristopher M Niell, Michael P Stryker
Aug 15, 2008·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Moritz HelmstaedterDirk Feldmeyer
Aug 20, 2007·Optics Express·Karsten BahlmannKarl Bellve
Sep 3, 2007·Optics Express·Ki Hean KimPeter T C So
Jul 22, 2009·Biophysical Journal·Joshua T VogelsteinLiam Paninski
Jul 29, 2009·Frontiers in Neural Circuits·Brendon O WatsonRafael Yuste
Sep 26, 2009·Neuron·Eran A MukamelMark J Schnitzer
Jun 18, 2010·Journal of Neurophysiology·Joshua T VogelsteinLiam Paninski
Jul 1, 2010·Optics Express·Paul A KirkbyR Angus Silver
Oct 14, 2010·Optics Express·Marco Dal MaschioTommaso Fellin
Jan 11, 2011·Nature Methods·Adrian ChengCarlos Portera-Cailliau
Jul 14, 2011·Biomedical Optics Express·Benjamin F GreweFritjof Helmchen
Aug 13, 2011·Neuron·Nathalie L RochefortArthur Konnerth
Aug 16, 2011·Trends in Neurosciences·Andrew D Huberman, Cristopher M Niell
Sep 29, 2011·Proceedings of the National Academy of Sciences of the United States of America·Hanno S MeyerMoritz Helmstaedter
Nov 15, 2011·Proceedings of the National Academy of Sciences of the United States of America·Francesca AnselmiValentina Emiliani
Feb 9, 2012·Proceedings of the National Academy of Sciences of the United States of America·Edward J BotcherbyTony Wilson
Jun 26, 2012·Neuron·A Paul AlivisatosRafael Yuste
Nov 13, 2012·Nature Methods·Adam M PackerRafael Yuste
Feb 8, 2013·Optics Express·Gregor ThalhammerMonika Ritsch-Marte
Mar 9, 2013·Science·A Paul AlivisatosRafael Yuste
Mar 22, 2013·ACS Nano·A Paul AlivisatosXiaowei Zhuang
Mar 26, 2013·Nature Methods·Misha B AhrensPhilipp J Keller
May 11, 2013·Science·Thomas R InselFrancis S Collins
Jun 27, 2013·Proceedings of the National Academy of Sciences of the United States of America·Mathieu DucrosSerge Charpak
Oct 18, 2013·Frontiers in Neural Circuits·R James CottonAndreas S Tolias
Apr 8, 2014·Neural Networks : the Official Journal of the International Neural Network Society·Ryuichi MaruyamaToru Aonishi
Apr 29, 2014·Frontiers in Neural Circuits·Sean QuirinRafael Yuste

❮ Previous
Next ❯

Citations

Mar 24, 2016·IEEE Transactions on Bio-medical Engineering·Chet T MoritzRajesh P N Rao
Oct 5, 2016·Biomedical Optics Express·Lingjie KongMeng Cui
Nov 1, 2016·Nature Methods·K M Naga Srinivas NadellaR Angus Silver
Nov 1, 2016·Nature Methods·Robert PrevedelAlipasha Vaziri
Jul 13, 2016·Scientific Reports·Francesco Paolo Ulloa SeverinoVincent Torre
Mar 21, 2017·Nature Methods·Alexander SongDavid W Tank
Apr 1, 2017·Nature Methods·Weijian Yang, Rafael Yuste
Nov 23, 2017·Journal of Biophotonics·Luiza FilipisMarco Canepari
May 2, 2018·Annual Review of Neuroscience·Siegfried Weisenburger, Alipasha Vaziri
Aug 5, 2017·PLoS Computational Biology·Johannes FriedrichLiam Paninski
Aug 30, 2016·Nature Neuroscience·Na JiSpencer L Smith
Aug 30, 2016·Nature Neuroscience·Kenneth D HarrisSpencer L Smith
Nov 11, 2016·Nature·Amber Dance
Dec 13, 2019·Biochemical Society Transactions·Xiaohong PengLiangyi Chen
Dec 17, 2019·Science Advances·Jaewook ShinMark A Foster
Nov 11, 2017·Brain Structure & Function·Jiangheng GuanXiang Liao
Mar 17, 2017·Annual Review of Biophysics·Luis Carrillo-ReidRafael Yuste
May 8, 2018·Nature Methods·Oliver SkocekAlipasha Vaziri
Feb 19, 2019·Biomedical Optics Express·Ee Zhuan ChongMartin J Booth
Jul 31, 2019·Biomedical Optics Express·Kayvan Forouhesh TehraniLuke J Mortensen
Apr 11, 2018·Frontiers in Cellular Neuroscience·L Federico RossiRobert C Wykes
Aug 1, 2019·Nature Methods·Abbas KazemipourKaspar Podgorski
Nov 16, 2019·Lasers in Medical Science·Pranoy Sahu, Nirmal Mazumder
Feb 12, 2020·Nature Methods·Devin R BeaulieuJerome Mertz
Dec 5, 2019·Biomedical Optics Express·Kevin T TakasakiJack Waters
Oct 27, 2017·Scientific Reports·David C Schedl, Oliver Bimber
Jul 20, 2019·Science·James H MarshelKarl Deisseroth
Jun 3, 2020·Nature Methods·Victoria A GriffithsR Angus Silver
Sep 11, 2020·Optics Express·Zongyue ChengMeng Cui
May 23, 2018·Scientific Reports·Sheng XiaoJerome Mertz

❮ Previous
Next ❯

Related Concepts

Related Feeds

Brain developing: Influences & Outcomes

This feed focuses on influences that affect the developing brain including genetics, fetal development, prenatal care, and gene-environment interactions. Here is the latest research in this field.