Simultaneous multislice diffusion-weighted imaging in whole-body positron emission tomography/magnetic resonance imaging for multiparametric examination in oncological patients

European Radiology
Jana TaronFerdinand Seith

Abstract

The aim of this study was to compare the diagnostic performance of simultaneous multislice diffusion-weighted imaging (DWI-SMS) with that of standard DWI (DWI-STD) in whole-body 3-T PET/MRI examination protocols in oncological patients. In a phantom study, we evaluated the apparent diffusion coefficients (ADC) from the two techniques. In ten volunteers, we assessed ADC values in different organs. In 20 oncological patients, we evaluated subjective image quality (Likert scale, 5 indicating excellent) and artefacts in different body regions. We also rated the conspicuity and acquired the ADC values of PET-positive tumorous lesions. The scan time for the whole-body DWI-SMS examinations was 40% shorter than the scan time for the DWI-STD examinations (84 s vs. 140 s per table position). The phantom and volunteer studies showed lower ADC values from DWI-SMS in the liver and muscle (psoas muscle 1.4 vs. 1.3). In patients, DWI-SMS provided poorer subjective image quality in the thoracoabdominal region (3.0 vs. 3.8, p = 0.02) and overall more artefacts (138 vs. 105). No significant differences regarding conspicuity and ADC values of lesions were found. DWI-SMS seems to provide reliable conspicuity and ADC values of tumorous lesions simi...Continue Reading

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Citations

Aug 14, 2020·European Radiology·Jeong Hee YoonJeong Min Lee
Dec 12, 2018·European Journal of Nuclear Medicine and Molecular Imaging·Christian Philipp ReinertSergios Gatidis
Jan 1, 2021·Journal of Magnetic Resonance Imaging : JMRI·Sandy Van NieuwenhoveFrederic E Lecouvet

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