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Simultaneous optogenetic manipulation and calcium imaging in freely moving C. elegans

bioRxiv

Nov 27, 2013

Frederick B. ShipleyAndrew Michael Leifer

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Abstract

A fundamental goal of systems neuroscience is to probe the dynamics of neural activity that drive behavior. Here we present an instrument to simultaneously manipulate neural activity via Channelrhodopsin, monitor neural response via GCaMP3, and observes behavior in freely moving C. eleg...read more

Mentioned in this Paper

Calcium
Diagnostic Imaging
Interneurons
Locomotion
Caenorhabditis elegans
Calcium Measurement
Cunninghamella elegans
Cyprinodon elegans
Instrument - Device
Codonanthe elegans
4
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  • Simultaneous optogenetic manipulation and calcium imaging in freely moving C. elegans

    bioRxiv

    Nov 27, 2013

    Frederick B. ShipleyAndrew Michael Leifer

    PMID: 990000943

    DOI: 10.1101/000943

    Abstract

    A fundamental goal of systems neuroscience is to probe the dynamics of neural activity that drive behavior. Here we present an instrument to simultaneously manipulate neural activity via Channelrhodopsin, monitor neural response via GCaMP3, and observes behavior in freely moving C. eleg...read more

    Mentioned in this Paper

    Calcium
    Diagnostic Imaging
    Interneurons
    Locomotion
    Caenorhabditis elegans
    4

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