Single- and dual-site pace mapping of idiopathic septal intramural ventricular arrhythmias

Heart Rhythm : the Official Journal of the Heart Rhythm Society
Miki YokokawaFrank Bogun

Abstract

Pace mapping (PM) is used to identify the origin of ventricular arrhythmias (VAs). For intramural VAs, the site of origin often cannot be reached and therefore PM is less accurate. The purpose of this study was to assess the value of single- and dual-site pace maps to differentiate intramural from nonintramural VAs. In 18 consecutive patients with idiopathic intramural VAs, pace mapping was performed at 2 breakthrough sites in adjacent anatomic structures. Twelve-lead electrocardiograms of the 2 pace maps were averaged in MATLAB and compared (correlation coefficient [CC]) with the targeted VA. Dual-site pace mapping was performed in a control group of 18 patients with nonintramural VAs at the sites of earliest electrical activation and a breakthrough site in an adjacent anatomic location. Dual-site pace maps had a higher CC than did best single-site pace maps (0.87 ± 0.1 vs 0.81 ± 0.16; P = .02) in patients with intramural VAs. At the site of origin, single-site pace maps had a higher CC than did dual-site pace maps obtained from adjacent anatomic locations (0.93 ± 0.04 vs 0.89 ± 0.05; P = .0004) in patients with nonintramural VAs. Sensitivity, specificity, positive predictive value, and negative predictive value of dual-site p...Continue Reading

Citations

Sep 20, 2015·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Jayanthi N Koneru, Kenneth A Ellenbogen
Sep 15, 2016·Circulation. Arrhythmia and Electrophysiology·Pasquale Santangeli, David J Callans
May 11, 2019·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Edmond M CroninUNKNOWN ESC Scientific Document Group
Jan 28, 2020·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·Edmond M CroninKatja Zeppenfeld
Oct 31, 2020·JACC. Clinical Electrophysiology·Michael GhannamFrank Bogun

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