Single-Cell Genomics and Epigenomics: Technologies and Applications in Plants

Trends in Plant Science
Cheng LuoJianbing Yan

Abstract

The development of genomics and epigenomics has allowed rapid advances in our understanding of plant biology. However, conventional bulk analysis dilutes cell-specific information by providing only average information, thereby limiting the resolution of genomic and functional genomic studies. Recent advances in single-cell sequencing technology concerning genomics and epigenomics open new avenues to dissect cell heterogeneity in multiple biological processes. Recent applications of these approaches to plants have provided exciting insights into diverse biological questions. We highlight the methodologies underlying the current techniques of single-cell genomics and epigenomics before covering their recent applications, potential significance, and future perspectives in plant biology.

Citations

Jun 28, 2020·Genome Biology·Qing Li, Jianbing Yan
Dec 2, 2020·International Journal of Molecular Sciences·Leonardo Perez de SouzaAlisdair Fernie
Dec 16, 2020·Proceedings of the National Academy of Sciences of the United States of America·James W SatterleeMichael J Scanlon
Nov 18, 2020·Journal of Plant Physiology·Jie LiuJianbing Yan
Apr 2, 2021·Frontiers in Bioengineering and Biotechnology·Rosa SagitaKristina Haslinger
May 8, 2021·Nature Genetics·Michael D Purugganan, Scott A Jackson
May 10, 2021·Current Opinion in Plant Biology·Yanlin ShaoHao Yu
Jun 12, 2021·Current Opinion in Plant Biology·Abbas ShojaeeShao-Shan Carol Huang
May 26, 2021·Plant Biotechnology Journal·Dandan HuJun Zou
May 25, 2021·Integrative and Comparative Biology·Edmund D BrodieNicole C Riddle
Apr 14, 2021·Plant Physiology·Alisdair R FernieJianbing Yan
Aug 28, 2021·Biology·Ioanna KakoulidouStéphane Maury
Oct 8, 2021·Cell Biology and Toxicology·Boyuan Zhao, Yonggang Lv

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