Single-cell RNA-seq of cultured human adipose-derived mesenchymal stem cells

Scientific Data
Xuanyu LiuZhou Zhou

Abstract

Adipose-derived mesenchymal stem cells (ADSCs) show considerable promise for clinical applications in regenerative medicine. We performed a large-scale single-cell transcriptomic sequencing of 24,358 cultured human ADSCs from three donors. We provide a high-quality dataset, which would be a valuable resource for dissecting the intrapopulation heterogeneity of cultured ADSCs as well as interrogating lineage priming patterns for any interested lineages at single-cell resolution.

References

Feb 21, 2006·Trends in Biotechnology·John K FraserMarc H Hedrick
May 15, 2007·Circulation Research·Jeffrey M GimbleBruce A Bunnell
Mar 29, 2008·Methods in Molecular Biology·John K FraserZeni Alfonso
Apr 19, 2012·Journal of Cellular Biochemistry·Donald G Phinney
Nov 8, 2014·Nucleic Acids Research·Alberto SantosLars Juhl Jensen
Mar 24, 2015·Bioscience Reports·Imran UllahGyu Jin Rho
May 26, 2015·Trends in Cell Biology·Rachael A NimmoTariq Enver
Feb 3, 2016·International Wound Journal·Naghmeh NaderiIain S Whitaker
Feb 19, 2016·Genome Biology·Tomislav IlicicSarah A Teichmann
Apr 17, 2016·Genome Biology·Lu Wen, Fuchou Tang
Jan 17, 2017·Nature Communications·Grace X Y ZhengJason H Bielas

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Citations

Sep 25, 2019·Cells·Irina V KholodenkoKonstantin N Yarygin
Jun 18, 2020·World Journal of Stem Cells·Guo-Ping XuEr-Man Chen
Aug 4, 2020·World Journal of Stem Cells·Guan ZhengHui-Yong Shen
Aug 1, 2020·Frontiers in Cell and Developmental Biology·Anny W RobertPatrícia Shigunov
Jun 17, 2020·The Biochemical Journal·Alice E Pollard, David Carling
Jun 26, 2020·International Journal of Molecular Sciences·Pyotr A Tyurin-KuzminVsevolod A Tkachuk
Dec 24, 2019·Trends in Cell Biology·Bing-Dong SuiCheng-Hu Hu
Jun 6, 2021·BMC Genomics·Sébastien RiquierThérèse Commes
Sep 24, 2021·BMC Genomics·N M PrashantAnelia Horvath
Oct 5, 2021·Frontiers in Cell and Developmental Biology·Wasco WruckJames Adjaye

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Datasets Mentioned

BETA
SRP148833

Methods Mentioned

BETA
RNA-seq
Chips

Software Mentioned

R package scran
cellranger aggr
Seurat
cellranger mkfastq

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