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Single-Cell RNA Sequencing of hESC-Derived 3D Retinal Organoids Reveals Novel Genes Regulating RPC Commitment in Early Human Retinogenesis

Stem Cell Reports

Oct 8, 2019

Xiying MaoGuoping Fan

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Abstract

The development of the mammalian retina is a complicated process involving the generation of distinct types of neurons from retinal progenitor cells (RPCs) in a spatiotemporal-specific manner. The progression of RPCs during retinogenesis includes RPC proliferation, cell-fate commitment,...read more

Mentioned in this Paper

Cell Cycle
Genes
Neurons
Organoids
Stem Cells
Subtype (Attribute)
Three-dimensional
Neurogenesis
Commitment
Sequence Determinations, RNA
13
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18
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Single-Cell RNA Sequencing of hESC-Derived 3D Retinal Organoids Reveals Novel Genes Regulating RPC Commitment in Early Human Retinogenesis

Stem Cell Reports

Oct 8, 2019

Xiying MaoGuoping Fan

PMID: 31543471

DOI: 10.1016/j.stemcr.2019.08.012

Abstract

The development of the mammalian retina is a complicated process involving the generation of distinct types of neurons from retinal progenitor cells (RPCs) in a spatiotemporal-specific manner. The progression of RPCs during retinogenesis includes RPC proliferation, cell-fate commitment,...read more

Mentioned in this Paper

Cell Cycle
Genes
Neurons
Organoids
Stem Cells
13
1
18

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