PMID: 2071153Jun 1, 1991Paper

Single-copy flanking sequences in human histone gene clusters map to chromosomes 1 and 6

Genomics
B S AllenH Ostrer

Abstract

Two single-copy sequences flanking two different human histone gene clusters were used as probes to map these clusters by in situ hybridization. pFF435B, a unique sequence subclone derived from a lambda genomic clone (lambda HHG55) containing H2A, H2B, H3, and H4 genes, mapped to chromosome 1q21 (chi 2 = 120.99, P less than 0.001). pST519E, a single-copy sequence derived from a lambda genomic clone (lambda HHG17) containing only H3 and H4 genes, mapped to chromosome 6p21 (chi 2 = 112.62, P less than 0.001). These findings agree with previous assignments of human histone genes to chromosomes 1 and 6 and demonstrate that the single-copy flanking sequences in different human histone gene clusters are unique for different chromosomes.

References

May 1, 1986·Proceedings of the National Academy of Sciences of the United States of America·P TripputiJ L Stein

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Citations

Apr 1, 1996·Human Genetics·W AlbigD Doenecke
Nov 26, 1999·Gene·Z Dominski, W F Marzluff
Dec 31, 2009·The Plant Cell·Sebastian ProostKlaas Vandepoele
Mar 4, 1999·Biological Chemistry·W AlbigD Doenecke
Nov 11, 2006·Journal of Cellular Physiology·Klaus A BeckerGary S Stein

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