Single-dose del Nido cardioplegia used in adult minimally invasive valve surgery

Journal of Thoracic Disease
Haiyan LuoXin Li

Abstract

To analyze the protective effect of single-dose del Nido cardioplegia (DNC) in adult minimally invasive valve surgery. From January to December 2017, 165 consecutive adult patients who underwent minimally invasive valve surgery by the same team of surgeons were divided into two cohorts based on the type of cardioplegia administered during surgery: (I) single-dose DNC (DNC group (n=76, male 41, female 35) used in patients from May to December, 2017 and (II) intermittent standard 4:1 blood cardioplegia based on St.Thomas solution (SBC group, n=89, male 45, female 44) used in patients from January to April, 2017. Preoperative baseline demographics, preoperative comorbidities, operative variables, postoperative complications, and patient outcomes were collected and compared between the two groups. Preoperative characteristics were shown to be similar between the two groups before and after propensity matching. Patients in the DNC group required a significantly lower volume of cardioplegia. The volume of ultrafiltration in the DNC group was substantially higher than that in the SBC group. The spontaneous return of heartbeat rate in the DNC group was considerably higher than that in the SBC group (97.0% vs. 78.8%, P=0.006). The Euros...Continue Reading

Citations

Sep 18, 2020·Innovations : Technology and Techniques in Cardiothoracic and Vascular Surgery·Ali Fatehi HassanabadWilliam D T Kent
May 10, 2020·BMC Cardiovascular Disorders·Mohamed MarzoukFrederic Jacques
Nov 7, 2020·Innovations : Technology and Techniques in Cardiothoracic and Vascular Surgery·Serdar GunaydinKanat Ozisik
Jun 4, 2021·Perfusion·Sion RussellHunaid A Vohra

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