Single dose diclofenac suppository reduces post-Cesarean PCEA requirements

Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie
N L LimA X Pan

Abstract

To assess the analgesic efficacy of administering, immediately after surgery, a single dose of diclofenac (100 mg suppository) to women who had undergone lower segment Cesarean section (LSCS) under combined spinal-epidural anesthesia, and received post-operative patient-controlled epidural analgesia (PCEA) with ropivacaine 0.2% and fentanyl 2 microg x ml(-1). Forty-eight ASA physical status I or II term parturients scheduled for elective LSCS under regional anesthesia were enrolled into this randomised double-blind study. The patient-controlled epidural analgesia device was programmed to deliver a bolus of 4 ml of local anesthetic mixture with a lockout period of ten minutes and an hourly limit of 12 ml. There was no baseline infusion. The study commenced upon the patient's first demand for analgesia post-operatively and the patients were assessed at one, six, 12 and 24 hr post-operatively for pain scores on movement, dermatomal level of sensory blockade, degree of motor blockade and volume of local anesthetic used. At conclusion of the study, patients' satisfaction scores were recorded. The two groups of patients were similar demographically. Patients who received a diclofenac suppository used 52.8 +/- 17.8 ml of local anesthe...Continue Reading

References

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Citations

Dec 18, 2001·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·B Biccard
Dec 25, 2012·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·R F FouladiA Abbassi
Feb 27, 2007·Journal of Clinical Anesthesia·Philip HuHenry Frizelle
Nov 18, 2009·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Nuray BozkurtKutay Biberoglu
Apr 6, 2013·Anesthesia and Analgesia·Melanie Bloor, Michael Paech

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