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Single dose pharmacokinetics and pharmacodynamics of oral oxazepam during concomitant administration of propranolol and labetalol

British Journal of Clinical Pharmacology

Jan 1, 1990

Jesper SonneH H Thyssen

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Abstract

1. The oral kinetics of oxazepam after a single 15 mg oral dose was investigated in six healthy volunteers before and during concomitant administration of the beta-adrenoceptor antagonists propranolol (80 mg) and labetalol (200 mg) (racemates). 2. A possible pharmacodynamic interaction ...read more

Mentioned in this Paper

Anticoagulants, Oral
Propranolol
Tazepam
Oxazepam
Speech Reception Threshold Test
Reaction Time
Biochemical Pathway
Drug Kinetics
Healthy Volunteers
Psychomotor Performance
Paper Details
References
  • References13
  • Citations3

Single dose pharmacokinetics and pharmacodynamics of oral oxazepam during concomitant administration of propranolol and labetalol

British Journal of Clinical Pharmacology

Jan 1, 1990

Jesper SonneH H Thyssen

PMID: 2297460

DOI: 10.1111/j.1365-2125.1990.tb03599.x

Abstract

1. The oral kinetics of oxazepam after a single 15 mg oral dose was investigated in six healthy volunteers before and during concomitant administration of the beta-adrenoceptor antagonists propranolol (80 mg) and labetalol (200 mg) (racemates). 2. A possible pharmacodynamic interaction ...read more

Mentioned in this Paper

Anticoagulants, Oral
Propranolol
Tazepam
Oxazepam
Speech Reception Threshold Test
Paper Details
References
  • References13
  • Citations3

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