Single-dose versus single-day antibiotic prophylaxis for orthognathic surgery: a prospective, randomized, double-blind clinical study

Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons
Anil Kumar DandaAvinash Siddareddi

Abstract

The purpose of this study was to evaluate the prophylactic value of single-dose antibiotic prophylaxis on postoperative infection in patients undergoing orthognathic surgery, compared to single-day antibiotics. One hundred fifty patients were included in the study; 57 males and 93 females were divided into 2 groups with 75 in each group. Group 1 received a single dose of antibiotic prophylaxis and group 2 received a single day of antibiotic prophylaxis. These patients were assessed for rates of infection postoperatively after orthognathic surgery. Seven patients (9.3%) in group 1 developed infection, whereas 2 patients (2.6%) in group 2 developed infection. The difference in rates of infection in both groups was of interest but not statistically significant (P > .05). The results from the present study show that there is a clinically significant difference, but no statistically significant difference, between single-dose antibiotic prophylaxis and single-day antibiotic prophylaxis in reducing the rates of infection in orthognathic procedures. We recommend further studies with a larger sample size to determine whether there truly is no statistical difference between both groups.

References

Apr 1, 1991·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·J M HeitR C Edwards
Jun 1, 1990·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·L J Peterson
Mar 17, 1999·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·K C BentleyG A Aiello

❮ Previous
Next ❯

Citations

Apr 10, 2013·Asian Pacific Journal of Tropical Biomedicine·C Ramu, T V Padmanabhan
Feb 27, 2016·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Clayton M DavisAmanda Demsey
Mar 7, 2014·International Journal of Oral and Maxillofacial Surgery·M A E M OomensT Forouzanfar
May 10, 2011·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Anil Kumar Danda, Poornima Ravi
Dec 21, 2010·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Su Keng TanRoger A Zwahlen
Oct 18, 2016·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Jeffrey C PosnickAnish Chavda
Nov 7, 2016·The Lancet Infectious Diseases·Benedetta AllegranziUNKNOWN WHO Guidelines Development Group
Jan 7, 2015·The Cochrane Database of Systematic Reviews·Romina Brignardello-PetersenJulio Villanueva
Aug 23, 2020·Plastic and Reconstructive Surgery·Christopher L KalmarJesse A Taylor
May 22, 2021·The British Journal of Oral & Maxillofacial Surgery·T MilicD Gebauer
Sep 2, 2021·The British Journal of Oral & Maxillofacial Surgery·A P S GilR B de Oliveira

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antifungals

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Antifungals (ASM)

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Related Papers

Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons
K C BentleyG A Aiello
The British Journal of Oral & Maxillofacial Surgery
Zaid H BaqainMalcolm Harris
Journal of Cranio-maxillo-facial Surgery : Official Publication of the European Association for Cranio-Maxillo-Facial Surgery
Yannick J E SpaeyLuc F Neyt
© 2021 Meta ULC. All rights reserved