Single-incision laparoscopic surgery for stricturing and penetrating Crohn's disease

Surgery Today
Tsunekazu MizushimaMasaki Mori

Abstract

Single-incision laparoscopic surgery (SILS) is a promising new technique that is potentially applicable to Crohn's disease (CD). However, there is no consensus on the application of SILS for penetrating CD due to its complex pathology. We investigated the feasibility of SILS in 24 CD patients (12 with stricturing and 12 with penetrating CD) and compared the results between the two groups. There were 17 males and seven females [median age at the time of surgery, 41 (range 20-61) years old] included in the study. Sixteen patients underwent primary surgery, while eight received repeat surgery. Twenty patients had small bowel CD and four patients had ileocolonic CD. The indication for surgery was a fistula/abscess in 12 patients, stenosis in 10 and other indications in two cases. The total length of the operation and blood loss was 171 min (113-221 min) and 230 mL (30-400 mL) in the penetrating CD cases, and 149 min (111-186 min) and 90 mL (20-400 mL) in the stricturing CD cases. There were no significant differences in the length of the operation between the two groups, but the blood loss was significantly greater in the cases of penetrating CD. Conversion to open surgery was required in one patient with penetrating CD. Postoperat...Continue Reading

References

May 14, 2004·The New England Journal of Medicine·UNKNOWN Clinical Outcomes of Surgical Therapy Study GroupDavid Ota
Jun 2, 2006·Surgical Endoscopy·A BelizonM E Sher
Dec 14, 2006·Digestive Surgery·Sebastiaan W PolleWillem A Bemelman
Dec 23, 2009·Inflammatory Bowel Diseases·Stefan D HolubarDavid W Larson
Feb 24, 2010·Surgical Endoscopy·Ichiro TakemasaMasaki Mori
Apr 8, 2010·Surgical Endoscopy·Kiyokazu NakajimaToshirou Nishida
Jan 10, 2012·Diseases of the Colon and Rectum·Emile RijckenMatthias Bruewer
Aug 28, 2012·Digestive Surgery·T J GardenbroekW A Bemelman
Apr 17, 2013·International Journal of Colorectal Disease·P A NeumannM Bruewer
Aug 14, 2013·The British Journal of Surgery·F BellolioR S McLeod

❮ Previous
Next ❯

Citations

Oct 21, 2016·Surgery Today·Rie MatsunagaMasaaki Ito
Aug 16, 2019·Journal of Laparoendoscopic & Advanced Surgical Techniques. Part a·Zhao-Liang YuXiao-Jian Wu
Feb 26, 2019·Surgery Today·Kiyoshi MaedaMasaichi Ohira

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.