PMID: 9168210May 1, 1997Paper

Single-injection lumbar epidural morphine for postoperative analgesia in children: a report of 175 cases

Regional Anesthesia
P BozkurtY Yeker

Abstract

Since the first report of epidural opioid administration to pediatric patients, several studies have described the quality of analgesia, doses, pharmacokinetics, and side effects of this procedure. A pediatric series using an easy and cheap single-injection technique of epidural morphine administration for postoperative analgesia is presented. Postoperative analgesia was achieved with a single lumbar epidural morphine injection (0.1 mg/kg in 0.2 mL/kg saline), which was given via a 22-gauge intramuscular needle to 153 pediatric patients (aged 4 months-17 years) following 175 lower abdominal or urologic operations. Injections were given by 43 anesthesiology residents under the supervision of pediatric anesthesiologists, after termination of surgery performed under general anesthesia. The success rate of epidural puncture on the first attempt was 92%. Pain control was considered excellent in 76% of patients for 24 hours. The remaining patients had analgesia lasting 10.9 +/- 5.5 hours after epidural morphine administration. No alterations in hemodynamic parameters were observed. Two patients (1.1%) developed respiratory depression during early postoperative care and one, with a history of apneic spells, had an episode of apnea 5 h...Continue Reading

Citations

Oct 3, 2006·Current Opinion in Anaesthesiology·G Allen Finley
Dec 7, 2006·Pain Practice : the Official Journal of World Institute of Pain·Bolkar E Sahinler
Jan 25, 2011·Expert Opinion on Pharmacotherapy·Wai Yin MakTheresa Hui
Jun 29, 2007·Paediatric Anaesthesia·Tina Hoff Duedahl, Ebba Holme Hansen
May 28, 2008·Paediatric Anaesthesia·Richard HowardUNKNOWN Association of Paediatric Anaesthetists of Great Britain and Ireland
May 17, 2008·Paediatric Anaesthesia·Johanna H A M MegensJohannes T A Knape
Jul 9, 2003·Paediatric Anaesthesia·Pervin BozkurtGulsev Kavunoglu
Sep 29, 1999·Pharmacology & Therapeutics·A R Lloyd-Thomas

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