Single lesion multibacillary leprosy, a treatment enigma: a case report.

Journal of Medical Case Reports
Bishwa R SapkotaRam K Maharjan

Abstract

Leprosy exhibits a wide spectrum of presentation, varying from the tuberculoid to the lepromatous pole, with immunologically unstable borderline forms in-between, depending upon the immune status of the individual. The clinical system of classification for the purpose of treatment includes the number of skin lesions and nerves involved as the basis for classifying the patients into multibacillary and paucibacillary. A 20-year-old man belonging to a moderately endemic leprosy area in the Terai region of Nepal reported a large single, hypopigmented, well defined anaesthetic lesion on his left thigh extending to his knee which had been present for 2 years. There was no other nerve involvement. Clinical diagnosis was tuberculoid leprosy and immunological lateral flow test for anti-Phenolic glycolipid-I antibody was positive. Six months of paucibacillary multidrug treatment was advised immediately. However, the patient was reclassified as multibacillary on the basis of a positive skin smear and appropriate treatment of 24 months multibacillary multidrug regimen was commenced after only 1 week. Slit skin smear examination for Mycobacterium leprae from the lesion revealed a bacterial index of 4+ while it was negative from the routine ...Continue Reading

References

Jun 26, 2004·International Journal of Leprosy and Other Mycobacterial Diseases : Official Organ of the International Leprosy Association·Bikash Ranjan KarC K Job
Jul 13, 2005·The Australasian Journal of Dermatology·Katherine S ArmourRoss StC Barnetson
Jun 12, 2008·Journal of Cutaneous Medicine and Surgery·Tarun NarangInderjeet Kaur

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Citations

Mar 2, 2010·The British Journal of Oral & Maxillofacial Surgery·K AliM A Malik

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Methods Mentioned

BETA
biopsy

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