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Single-molecule FRET reveals nucleotide-driven conformational changes in molecular machines and their link to RNA unwinding and DNA supercoiling

Biochemical Society Transactions

Mar 25, 2011

Dagmar Klostermeier

Abstract

Many complex cellular processes in the cell are catalysed at the expense of ATP hydrolysis. The enzymes involved bind and hydrolyse ATP and couple ATP hydrolysis to the catalysed process via cycles of nucleotide-driven conformational changes. In this review, I illustrate how smFRET (sin...read more

Mentioned in this Paper

RNA Conformation
Bacterial Proteins
Enzymes, antithrombotic
DEAD-box RNA Helicases
Topoisomerase
Enzymes for Treatment of Wounds and Ulcers
Topoisomerase Activity
Nucleotides
Natto Bacteria
DNA, Superhelical
Paper Details
References
  • References42
  • Citations6
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Single-molecule FRET reveals nucleotide-driven conformational changes in molecular machines and their link to RNA unwinding and DNA supercoiling

Biochemical Society Transactions

Mar 25, 2011

Dagmar Klostermeier

PMID: 21428949

DOI: 10.1042/bst0390611

Abstract

Many complex cellular processes in the cell are catalysed at the expense of ATP hydrolysis. The enzymes involved bind and hydrolyse ATP and couple ATP hydrolysis to the catalysed process via cycles of nucleotide-driven conformational changes. In this review, I illustrate how smFRET (sin...read more

Mentioned in this Paper

RNA Conformation
Bacterial Proteins
Enzymes, antithrombotic
DEAD-box RNA Helicases
Topoisomerase
Enzymes for Treatment of Wounds and Ulcers
Topoisomerase Activity
Nucleotides
Natto Bacteria
DNA, Superhelical

Related Papers

Paper Details
References
  • References42
  • Citations6
12345
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