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Single molecule-level detection and long read-based phasing of epigenetic variations in bacterial methylomes

bioRxiv

Sep 17, 2014

John BeaulaurierGang Fang

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Abstract

Comprehensive genome-wide analyses of bacterial DNA methylation have not been possible until the recent advent of single molecule, real-time (SMRT) sequencing. This technology enables the direct detection of N6-methyladenine (6mA) and 4-methylcytosine (4mC) at single nucleotide resoluti...read more

Mentioned in this Paper

Small Molecule
Study of Epigenetics
NCOR2 wt Allele
NCOR2 gene
Study
Evaluation
Genome Sequencing
2-methyladenine
5-Methylcytosine
Methyltransferase Activity
24
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  • Single molecule-level detection and long read-based phasing of epigenetic variations in bacterial methylomes

    bioRxiv

    Sep 17, 2014

    John BeaulaurierGang Fang

    PMID: 990007823

    DOI: 10.1101/007823

    Abstract

    Comprehensive genome-wide analyses of bacterial DNA methylation have not been possible until the recent advent of single molecule, real-time (SMRT) sequencing. This technology enables the direct detection of N6-methyladenine (6mA) and 4-methylcytosine (4mC) at single nucleotide resoluti...read more

    Mentioned in this Paper

    Small Molecule
    Study of Epigenetics
    NCOR2 wt Allele
    NCOR2 gene
    Study
    24

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