Single-nanoparticle near-infrared surface plasmon resonance microscopy for real-time measurements of DNA hybridization adsorption

ACS Nano
Aaron R HalpernRobert M Corn

Abstract

A novel 814 nm near-infrared surface plasmon resonance (SPR) microscope is used for the real-time detection of the sequence-selective hybridization adsorption of single DNA-functionalized gold nanoparticles. The objective-coupled, high numerical aperture SPR microscope is capable of imaging in situ the adsorption of single polystyrene and gold particles with diameters ranging from 450 to 20 nm onto a 90 μm × 70 μm area of a gold thin film with a time resolution of approximately 1-3 s. Initial real-time SPR imaging (SPRI) measurements were performed to detect the accumulation of 40 nm gold nanoparticles for 10 min onto a gold thin film functionalized with a 100% complementary DNA surface at concentrations from 5 pM to 100 fM by counting individual particle binding events. A 100% noncomplementary DNA surface exhibited virtually no nanoparticle adsorption. In contrast, in a second set of SPRI measurements, two component complementary/noncomplementary mixed DNA monolayers that contained a very small percentage of complementary sequences ranging from 0.1 to 0.001%, showed both permanent and transient hybridization adsorption of the gold nanoparticles that could be tracked both temporally and spatially with the SPR microscope. These ...Continue Reading

References

Dec 9, 1998·Analytical Chemistry·A B SteelM J Tarlov
Dec 30, 1998·Analytical Chemistry·L A LyonM J Natan
Oct 14, 2000·Annual Review of Physical Chemistry·J M BrockmanR M Corn
Jul 19, 2003·Applied Optics·Takuo Tanaka, Sadahiko Yamamoto
Dec 15, 2006·Analytical Chemistry·Sarah J HurstChad A Mirkin
Feb 21, 2007·Analytical Chemistry·Bo HuangRichard N Zare
Dec 8, 2007·Optics Letters·M G SomekhC W See
Mar 21, 2008·Applied Optics·M G SomekhC W See
Jul 10, 2008·Journal of Structural Biology·M Mahadi Abdul JamilJ Zhang
Mar 4, 2009·Langmuir : the ACS Journal of Surfaces and Colloids·Yulin ChenRobert M Corn
Oct 1, 2009·Langmuir : the ACS Journal of Surfaces and Colloids·Iuliana E SendroiuRobert M Corn
Jul 16, 2010·Cytometry. Part a : the Journal of the International Society for Analytical Cytology·Alexander W PetersonAnne L Plant
Aug 28, 2010·Proceedings of the National Academy of Sciences of the United States of America·Shaopeng WangNongjian Tao
Feb 9, 2012·Biomedical Optics Express·Koyo WatanabeHiroshi Kano
Mar 15, 2012·Macromolecular Bioscience·Erin E BedfordFrank X Gu
Aug 28, 2012·Langmuir : the ACS Journal of Surfaces and Colloids·Wei WangNongjian Tao
Aug 28, 2012·Nature Nanotechnology·Xiaonan ShanNongjian Tao
Apr 9, 2013·Analytica Chimica Acta·Hana Šípová, Jiří Homola

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Citations

Aug 19, 2014·Nanoscale·Antonio Politano, Gennaro Chiarello
Jan 15, 2016·Analytical Chemistry·Simon ForestJean-Francois Masson
Dec 17, 2015·Scientific Reports·Angela Demetriadou
Jan 26, 2016·Chemical Society Reviews·Joshua B EdelMichael Urbakh
Apr 22, 2015·Trends in Biotechnology·Marina CretichMarcella Chiari
Aug 10, 2016·Applied Optics·Alexander FastEric O Potma
Mar 31, 2015·Journal of Laboratory Automation·Yung-Shin Sun
Feb 21, 2019·Proceedings of the National Academy of Sciences of the United States of America·Derin SevenlerM Selim Ünlü
Mar 17, 2017·Annual Review of Analytical Chemistry·Liang YuanWei Wang
Aug 6, 2020·Optics Express·Jingkai Ji, Libo Yuan
May 29, 2018·Optics Express·John P KenisonEric Olaf Potma
Jun 14, 2019·Proceedings of the National Academy of Sciences of the United States of America·Jing ChenWei Wang
Jul 16, 2020·Proceedings of the National Academy of Sciences of the United States of America·Hui WangNongjian Tao
Mar 16, 2019·Proceedings of the National Academy of Sciences of the United States of America·Yingyan JiangWei Wang
Apr 14, 2018·Analytical and Bioanalytical Chemistry·Yu-Wen Su, Wei Wang
Sep 20, 2017·Proceedings of the National Academy of Sciences of the United States of America·Yimin FangWei Wang
Feb 19, 2021·The Journal of Physical Chemistry Letters·Yunshan FanRobert M Corn
Apr 16, 2021·The Journal of Physical Chemistry Letters·Zhiheng YangXuefeng Guo
Aug 23, 2018·Analytical Chemistry·Alexey KuzmichevRoland Hergenröder
Jul 15, 2017·The Journal of Physical Chemistry. C, Nanomaterials and Interfaces·Gerald ManuelRobert M Corn

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