Single olivocochlear neurons in the guinea pig. I. Binaural facilitation of responses to high-level noise

Journal of Neurophysiology
M C BrownM L Duca

Abstract

Single medial olivocochlear (MOC) neurons were recorded from the cochlea of the anesthetized guinea pig. We used tones and noise presented monaurally and binaurally and measured responses for sounds up to 105 dB sound pressure level (SPL). For monaural sound, MOC neuron firing rates were usually higher for noise bursts than tone bursts, a situation not observed for afferent fibers of the auditory nerve that were sampled in the same preparations. MOC neurons also differed from afferent fibers in having less saturation of response. Some MOC neurons had responses that continued to increase even at high sound levels. Differences between MOC and afferent responses suggest that there is convergence in the pathway to olivocochlear neurons, possibly a combination of inputs that are at the characteristic frequency (CF) with others that are off the CF. Opposite-ear noise almost always facilitated the responses of MOC neurons to sounds in the main ear, the ear that best drives the unit. This binaural facilitation depends on several characteristics that pertain to the main ear: it is higher in neurons having a contralateral main ear (contra units), it is higher at main-ear sound levels that are moderate (approximately 65 dB SPL), and it is...Continue Reading

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Citations

Nov 9, 2000·Microscopy Research and Technique·R B IllingS A Michler
Jun 15, 2004·Neuroreport·Matthieu J GuittonPierre Bonfils
Mar 6, 2009·Journal of the Association for Research in Otolaryngology : JARO·Watjana Lilaonitkul, John J Guinan
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Feb 24, 2015·The Journal of the Acoustical Society of America·Sriram Boothalingam, David W Purcell
Dec 29, 2010·Hearing Research·Eric Wersinger, Paul Albert Fuchs

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