Single-photon emission tomography imaging in patients with Lyme disease treated with human embryonic stem cells

The Neuroradiology Journal
Geeta Shroff

Abstract

Aim The purpose of this study was to evaluate the longitudinal changes in brain perfusion in patients with Lyme disease treated with human embryonic stem cells. Material and methods The study included 59 (age range 41.68 ± 16.37 years) patients with Lyme disease whose single-photon emission tomography imaging was performed before and after the human embryonic stem cell therapy. Technetium-hexa methyl propylene aminoxime single-photon emission tomography imaging was used to assess the hypoperfused lesions/regions in the brain prior to the therapy, as well as the improvement in perfusion after human embryonic stem cell treatment. Results After receiving human embryonic stem cell therapy, single-photon emission tomography imaging reflects a significant (>60%) improvement in 43 patients along with moderate (30-60%) and mild (<30%) improvement in 12 and four patients, respectively. The cerebral perfusion flow improved and the degree of hypoperfusion in the other regions significantly decreased after the human embryonic stem cell therapy. Interpretation of single-photon emission tomography imaging of brain images (before and after therapy) clearly presented the changes in color at various brain regions which represent the improvement...Continue Reading

References

Nov 1, 1994·The American Journal of Psychiatry·B A Fallon, J A Nields
Jul 1, 1997·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·B A FallonR Van Heertum
Jun 9, 1998·Annals of the New York Academy of Sciences·D A Silbersweig, E Stern
Jul 25, 2000·Laboratory Investigation; a Journal of Technical Methods and Pathology·D CadavidA R Pachner
May 2, 2002·The Medical Clinics of North America·Sam T Donta
Nov 18, 2008·Medical Hypotheses·Daniel J Cameron
Aug 25, 2011·The Open Neuroimaging Journal·Daniel G AmenBarry Chaitin
Aug 15, 2012·Clinical Nuclear Medicine·Sam T DontaJohn A Vento
Apr 9, 2013·Future Neurology·Mibel M Pabon, Cesar V Borlongan
Jun 1, 2013·Indian Journal of Dermatology·Biju Vasudevan, Manas Chatterjee
Jun 25, 2014·BioMed Research International·Leif ClaassenChristian Plaass
Dec 17, 2014·Journal of Translational Medicine·Geeta ShroffJitender Kumar Barthakur
Nov 4, 2015·Annals of Neurosciences·Geeta Shroff, Rakesh Gupta

❮ Previous
Next ❯

Citations


❮ Previous
Next ❯

Methods Mentioned

BETA
imaging techniques
imaging technique

Software Mentioned

NeuroGam )

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.