Single-Session CT-Guided Percutaneous Microwave Ablation of Bilateral Adrenal Gland Hyperplasia Due to Ectopic ACTH Syndrome

Cardiovascular and Interventional Radiology
Asha SarmaStuart G Silverman

Abstract

Bilateral adrenalectomy is currently the only available treatment for adrenocorticotropic hormone (ACTH)-dependent Cushing's syndrome (ectopic ACTH syndrome) that is refractory to pharmacologic therapy. We describe two patients with refractory ectopic ACTH syndrome who were treated with CT-guided percutaneous microwave ablation of both hyperplastic adrenal glands in a single session: O ne was not a surgical candidate, and the other had undergone unsuccessful surgery. Following the procedure, both patients achieved substantial decreases in serum cortisol, symptomatic improvement, and decreased anti-hypertensive medication requirements.

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Citations

Oct 24, 2020·Journal of Clinical Imaging Science·Grzegorz RosiakWojciech Zgliczynski
Aug 28, 2021·Journal of Neuroendocrinology·Ieva LaseEva Tiensuu Janson

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