Single-session endoscopic resection and focal radiofrequency ablation for short-segment Barrett's esophagus with early neoplasia

Gastrointestinal Endoscopy
Maximilien BarretRoos E Pouw

Abstract

The management of early neoplasia in Barrett's esophagus (BE) requires endoscopic resection of visible lesions, followed by radiofrequency ablation (RFA) of the remaining BE. We evaluated the safety and efficacy of combining endoscopic resection and focal RFA in a single endoscopic session in patients with early BE neoplasia. This was a retrospective analysis of patients with early BE neoplasia and a visible lesion undergoing combined endoscopic resection and focal RFA in a single session. Consecutive ablation procedures were performed every 8 to 12 weeks until complete endoscopic and histologic eradication of dysplasia and intestinal metaplasia were reached. Forty patients were enrolled, with a median C1M2 BE segment, a visible lesion with a median diameter of 15 mm, and invasive carcinoma in 68% of cases. Endoscopic resection was performed by using the multiband mucosectomy technique in 80% of cases, and the Barrx(90) catheter (Barrx Medical, Sunnyvale, Calif) was used for focal ablation. When an intention-to-treat analysis was used, both complete remission of all neoplasia and intestinal metaplasia were 95% after a median follow-up of 19 months. Stenoses occurred in 33% of cases and were successfully managed with a median nu...Continue Reading

References

Mar 3, 2011·Endoscopy·L Alvarez HerreroJ J G H M Bergman
Mar 8, 2011·Gastroenterology·Stuart J SpechlerUNKNOWN American Gastroenterological Association
Jun 18, 2011·Gastroenterology·Nicholas J ShaheenCharles J Lightdale

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Citations

Aug 18, 2017·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Yuto ShimamuraChristopher W Teshima
Oct 5, 2018·World Journal of Gastrointestinal Endoscopy·Tavankit SinghPrashanthi N Thota
Nov 4, 2020·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·S N van MunsterUNKNOWN Dutch Barrett Expert Centers

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