Single-Staged Compared With Multi-Staged PCI in Multivessel NSTEMI Patients: The SMILE Trial

Journal of the American College of Cardiology
Gennaro SardellaMassimo Mancone

Abstract

A lack of clarity exists about the role of complete coronary revascularization in patients presenting with non-ST-segment elevation myocardial infarction. The aim of our study was to compare long-term outcomes in terms of major adverse cardiovascular and cerebrovascular events of 2 different complete coronary revascularization strategies in patients with non-ST-segment elevation myocardial infarction and multivessel coronary artery disease: 1-stage percutaneous coronary intervention (1S-PCI) during the index procedure versus multistage percutaneous coronary intervention (MS-PCI) complete coronary revascularization during the index hospitalization. In the SMILE (Impact of Different Treatment in Multivessel Non ST Elevation Myocardial Infarction Patients: One Stage Versus Multistaged Percutaneous Coronary Intervention) trial, 584 patients were randomly assigned in a 1:1 manner to 1S-PCI or MS-PCI. The primary study endpoint was the incidence of major adverse cardiovascular and cerebrovascular events, which were defined as cardiac death, death, reinfarction, rehospitalization for unstable angina, repeat coronary revascularization (target vessel revascularization), and stroke at 1 year. The occurrence of the primary endpoint was si...Continue Reading

References

Sep 25, 2004·American Heart Journal·Alexander J J IjsselmuidenGertJan Laarman
Dec 18, 2007·American Heart Journal·Sorin J BrenerUNKNOWN American College of Cardiology National Cardiovascular Database Registry
Sep 11, 2012·Journal of the American College of Cardiology·Kristian ThygesenDaniel R Wagner
Sep 3, 2013·The New England Journal of Medicine·David S WaldUNKNOWN PRAMI Investigators
Sep 27, 2014·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Stephan WindeckerJose L Zamorano
Dec 1, 2012·Global Heart·Kristian ThygesenHarvey D White

❮ Previous
Next ❯

Citations

Feb 25, 2017·Journal of the American College of Cardiology·Valentin Fuster
Oct 31, 2017·The New England Journal of Medicine·Holger ThieleUNKNOWN CULPRIT-SHOCK Investigators
Oct 1, 2017·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·M Bilal IqbalUNKNOWN Harefield Cardiac Outcomes Group Investigators
Apr 12, 2017·Journal of the American Heart Association·Rouan GaffarMark J Eisenberg
Apr 11, 2019·Current Cardiology Reports·Bennet GeorgeKhaled M Ziada
May 1, 2019·Circulation. Cardiovascular Interventions·John F HeitnerRaymond J Kim
Sep 19, 2019·Netherlands Heart Journal : Monthly Journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation·T F S PustjensS Rasoul
Aug 30, 2020·European Heart Journal·Jean-Philippe ColletUNKNOWN ESC Scientific Document Group
Mar 30, 2018·Interventional Cardiology·Carlo De InnocentiisRaffaele De Caterina
Jan 23, 2019·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Franz-Josef NeumannMichael O Zembala
Jan 23, 2020·Netherlands Heart Journal : Monthly Journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation·R J de Winter
Aug 31, 2018·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Miguel Sousa-UvaUNKNOWN ESC Scientific Document Group
Mar 30, 2020·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Mohammad Saud KhanSohail Ikram
Nov 18, 2017·Heart·Toshiaki ToyotaUNKNOWN CREDO-Kyoto PCI/CABG Registry Cohort-2 Investigators
Jul 28, 2020·Current Cardiology Reports·Islam Y ElgendyDavid Paniagua
Jul 1, 2020·Heart and Vessels·Makoto SuzukiUNKNOWN JAMIR Investigators
Jul 11, 2020·Journal of the American Heart Association·Lucas Chun Wah FongColin Berry
Jan 4, 2017·European Heart Journal·Filippo CreaThomas F Lüscher
Aug 31, 2018·European Heart Journal·Franz-Josef NeumannUNKNOWN ESC Scientific Document Group
Apr 7, 2021·Korean Circulation Journal·Kiyuk ChangUNKNOWN Task Force on Expert Consensus Document of the Korean Society of Myocardial Infarction (KSMI)
Apr 12, 2021·Cardiovascular Revascularization Medicine : Including Molecular Interventions·Matthew Mercieca BalbiRoberto Diletti
Jun 26, 2021·Heart·Jorge Sanz-Sánchez, Giulio G Stefanini
Jun 26, 2021·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Valeria ParadiesPieter Cornelis Smits
Jun 27, 2021·The Egyptian Heart Journal : (EHJ) : Official Bulletin of the Egyptian Society of Cardiology·Ahmed O ElkadyAbdalla A Elagha
May 1, 2021·Current Opinion in Critical Care·Jakob JosiassenChristian Hassager
Jul 24, 2021·Journal of the American College of Cardiology·Patrick W SerruysSpencer B King Iii
Nov 14, 2021·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Jacqueline E Tamis-HollandJoaquin Cigarroa
Nov 25, 2021·Journal of the American Heart Association·Tatsuhiko OtsukaLorenz Räber

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiology Journals

Discover the latest cardiology research in this collection of the top cardiology journals.