PMID: 577669Jul 1, 1977Paper

Single-step gastric aspirate shake test: bedside predictor of neonatal pulmonary morbidity

Archives of Disease in Childhood
A K TanswellB T Smith


A simplified, single-step shake test has been performed on gastric aspirate samples from 85 preterm infants and a control group of 214 term infants. Respiratory symptoms were seen in 25 of 30 preterm infants with a negative or intermediate test, but in only 2 of 55 infants with a positive test (P less than 0-001). No infant with a positive test developed respiratory distress syndrome (RDS) while RDS developed in 66% of those preterm infants with a negative test. False-negative results were not seen in the preterm group. The gastric aspirate shake test had better sensitivity and selectivity in prediction of clinical outcome than did the amniotic fluid lecithin/sphingomyelin ratio in 37 preterm infants in whom both results were available. Serial shake tests were performed on samples from a number of infants with RDS and the results were seen to change in parallel with clinical recovery. This and other observations suggest that the result of the gastric aspirate shake test depends more upon direct swallowing of fetal lung liquid than on swallowing of amniotic fluid.


Aug 28, 1975·The New England Journal of Medicine·R M CowettW Oh
Jan 22, 1976·The New England Journal of Medicine·D O Gebhardt, J H Ruys
May 22, 1975·The New England Journal of Medicine·J J Evans
Jul 1, 1970·The Journal of Pediatrics·L M DubowitzC Goldberg
May 1, 1967·Respiration Physiology·F H AdamsB Towers

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Dec 29, 1977·The New England Journal of Medicine·A K Tanswell, B T Smith
Mar 1, 1981·Archives of Disease in Childhood·M L SmithF Forshaw
Dec 1, 1980·Early Human Development·W D Seybold, B T Smith
Jan 1, 1980·The Journal of Pediatrics·J JacobW F Friedman
Apr 12, 2012·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Sahar M A HassaneinNoha A E Abd El Rahman
Jun 1, 1994·Pediatric Pulmonology·R Skelton, H Jeffery

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