Single subcortical infarction associated with parental arterial disease: important yet neglected sub-type of atherothrombotic stroke

International Journal of Stroke : Official Journal of the International Stroke Society
Jong S Kim, Youngshin Yoon

Abstract

Traditionally, single subcortical infarction has been considered to be caused by lipohyalinosis of small perforating arteries. However, atherosclerosis in the parental artery produces similar single subcortical infarction by blocking the orifice of branching arteries. The purpose of this paper is to review the evolving concepts, clinical characteristics, and classification issues of single subcortical infarction associated with parental artery disease. Single subcortical infarction associated with parental artery disease is an important cause of subcortical infarction, more so in the posterior than in anterior circulation stroke. It is one of the major causes of brainstem infarction. Single subcortical infarction associated with parental artery disease seems to be common in Asian population where intracranial atherosclerosis is prevalent. Although the clinical characteristics of single subcortical infarction associated with parental artery disease are similar to single subcortical infarction caused by small artery disease, single subcortical infarction associated with parental artery disease is more often associated with characteristics of atherosclerosis, and fluctuating and poorer outcomes. With advanced imaging techniques su...Continue Reading

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Citations

Sep 21, 2015·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Yuan GaoYuming Xu
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Methods Mentioned

BETA
imaging techniques
PCA
dissection

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