PMID: 429008Jan 19, 1979Paper

Sister chromatid exchanges and aging. III. The effect of donor age on mutagen-induced sister chromatid exchange in human diploid fibroblasts

Human Genetics
E L Schneider, B A Gilman

Abstract

Although baseline levels of SCE appear to be similar in metaphase cells derived from young and old human skin fibroblast cultures, a significant decline in both MMC- and AAAF-induced sister chromatid exchanges was observed in the older cell populations. Considerable variation exists in the levels of MMC-induced SCE between individual cell cultures. However, parallel examination of several cell strains from young and old donors confirmed the decrease in mutagen-induced SCE frequencies in older cell populations.

References

Mar 1, 1978·Proceedings of the National Academy of Sciences of the United States of America·J R SmithE L Schneider
Oct 1, 1975·Proceedings of the National Academy of Sciences of the United States of America·S A LattP S Gerald
Oct 1, 1976·Proceedings of the National Academy of Sciences of the United States of America·E L Schneider, Y Mitsui
Jan 1, 1976·Mechanisms of Ageing and Development·R W Hart, R B Setlow
Dec 1, 1973·Proceedings of the National Academy of Sciences of the United States of America·S A Latt
Aug 5, 1974·Biochemical and Biophysical Research Communications·J EpsteinJ B Little
Apr 18, 1975·Science·R R Kohn

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Citations

Jan 1, 1980·International Archives of Occupational and Environmental Health·T WatanabeM Ikeda
May 26, 1981·Molecular and Cellular Biochemistry·M Reff, E L Schneider
Jul 18, 2009·Biogerontology·Alvaro Macieira-Coelho
Jul 7, 2011·Biogerontology·Alvaro Macieira-Coelho
Feb 1, 1979·Mechanisms of Ageing and Development·E L SchneiderM L Nieder
May 1, 1981·Mechanisms of Ageing and Development·M A Schmidt, W G Sanger
Oct 15, 1984·Mechanisms of Ageing and Development·A Macieira-Coelho
Sep 1, 1993·Mutation Research·J D TuckerA V Carrano
Jan 1, 1986·Experimental Gerontology·A Macieira-Coelho
Jan 1, 1996·Free Radical Biology & Medicine·B P Yu
Feb 1, 1987·Biological Reviews of the Cambridge Philosophical Society·S SenA Sharma
Jun 1, 1991·Journal of the American Geriatrics Society·A D Mooradian, N C Wong
Mar 25, 2008·DNA Repair·Dominika M Wiktor-BrownBevin P Engelward

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