PMID: 2511443Dec 1, 1989Paper

Sister-chromatid exchanges induced by mitomycin C after acute or chronic exposure of human lymphocytes to a low dose of X-rays

Mutation Research
J E MoquetD C Lloyd

Abstract

Human peripheral blood lymphocytes from 10 male donors were exposed to mitomycin C with and without prior irradiation with 0.01 Gy X-rays. Acute or chronic irradiation of lymphocytes in G1 resulted in a decrease in the subsequent level of mitomycin C-induced sister-chromatid exchange aberrations. The effect was small (approximately 10%) with evidence of some variability between donors. By contrast no adaptive response was observed if the cells were treated in G0.

References

May 19, 1977·Nature·L Samson, J Cairns
Mar 1, 1989·Mutation Research·K SankaranarayananA T Natarajan
Feb 1, 1984·Proceedings of the National Academy of Sciences of the United States of America·F Laval, J Laval

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Citations

Nov 26, 2002·International Journal of Cancer. Journal International Du Cancer·Octávia Monteiro GilJosé Rueff
Feb 1, 1992·Mutation Research·J D Shadley, G Q Dai
May 30, 1998·Biochemical Pharmacology·C Stecca, G B Gerber
Dec 25, 2013·Journal of Radiation Research·Masao S SasakiShunichi Takeda
Oct 1, 1990·International Journal of Radiation Biology·H TuschlA Wottawa
Jul 8, 2009·Radiation Research·Anna SanninoMaria Rosaria Scarfì
Apr 15, 2015·Physiological Reports·Shinya MasudaYusuke Ono

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