PMID: 8971986Nov 1, 1996Paper

Site of facilitation of diaphragm EMG to corticospinal stimulation during inspiration

Respiration Physiology
Nick J DaveyPeter H Ellaway

Abstract

The electromyographic response of the diaphragm to (a) transcutaneous electrical stimulation (TCES) of the spinal cord at C5 and above, (b) transcranial magnetic stimulation (TMS) over the motor cortex and (c) transcutaneous electrical stimulation of the phrenic nerve in the neck (TPNS), was recorded in six normal subjects at the antero-lateral chest wall. The compound motor evoked potentials (cMEPs) recorded in response to both TMS and TCES were facilitated to a similar extent during volitional inspiration; this facilitation was greater than any change seen in response to TPNS with inspiration. The results show that facilitation of the response in the diaphragm to TMS during volitional inspiration is due to increased excitability at synapses associated with the spinal motoneurone pool, but they do not exclude a component due to increased higher centre excitability. We conclude that it is unsafe to assign a cortical contribution to 'automatic' inspiration on the sole basis of facilitation of the electromyographic response in the diaphragm to TMS.

References

Sep 1, 1992·Annals of Neurology·A Maertens de NoordhoutP J Delwaide
Jan 1, 1989·Electroencephalography and Clinical Neurophysiology·R Lansing, J Savelle

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Citations

Mar 13, 2012·Translational Stroke Research·Daniela G L Terson de PalevilleAlexander V Ovechkin
Jul 31, 2007·Respiratory Physiology & Neurobiology·Jane E Butler
Sep 4, 2013·Respiratory Physiology & Neurobiology·Daniela Terson de PalevilleAlexander Ovechkin
Sep 2, 2016·Experimental Neurology·Kristiina M HormigoMichael A Lane
Jan 13, 2006·Respiratory Physiology & Neurobiology·Selma MehiriThomas Similowski
Aug 4, 2006·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·P A PaineS Hamdy
Mar 18, 2003·Journal of Applied Physiology·Tarek SharsharMichael I Polkey

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