PMID: 9426096Jan 13, 1998Paper

Site of upper airway obstruction in obstructive apnoea and influence of sleep stage

The European Respiratory Journal
An N BoudewynsWilfried De Backer

Abstract

Various sites along the upper airway (UA) are prone to narrow and collapse in patients affected by obstructive sleep apnoea. Sleep stages may eventually alter these sites. The present study was designed to determine the site(s) of UA obstruction and the influence of sleep stage on the pattern of obstruction. Twenty eight obstructive sleep apnoea patients underwent UA pressure measurements during polysomnography. Solid-state pressure sensors were located at the nasopharynx, oropharynx, tongue base, hypopharynx and oesophagus and the lower limit of UA obstruction was determined relying on the observed pressure pattern. The site of UA obstruction varied among consecutive apnoeas in all but two patients. The lower limit of UA obstruction was predominantly located at the nasoand oropharynx. Rapid eye movement (REM) sleep was associated with a tendency for obstruction to extend towards lower levels of the UA and nasopharyngeal occlusion was significantly less observed during REM compared to oropharyngeal obstruction. Upper airway obstruction involves more than one specific site of the upper airway in the majority of sleep apnoea patients. Obstruction at lower levels of the upper airway is more likely to be observed during rapid eye m...Continue Reading

Citations

Sep 24, 2002·Sleep & Breathing = Schlaf & Atmung·John S Viviano
Jan 19, 2012·Sleep & Breathing = Schlaf & Atmung·Shyam SubramanianSalim Surani
May 30, 2009·Respiration; International Review of Thoracic Diseases·Johan A Verbraecken, Wilfried A De Backer
Jun 17, 2010·IEEE Transactions on Bio-medical Engineering·A D LuceyD R Hillman
Aug 6, 2004·Cranio : the Journal of Craniomandibular Practice·John S Viviano
Jan 30, 2007·Respiration; International Review of Thoracic Diseases·A RazaA Bradford
May 19, 2010·Expert Review of Respiratory Medicine·Winfried J Randerath
Apr 8, 2011·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Kurt TschoppThomas Fabbro
Mar 11, 2003·Journal of Applied Physiology·Pierre-Hugues FortierJean-Paul Praud
Jun 16, 2001·Journal of Applied Physiology·J A RowleyM S Badr
Oct 14, 2003·Journal of Applied Physiology·Arie OlivenAlan R Schwartz
Oct 5, 2017·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Markus WirthClemens Heiser
Nov 16, 2002·Journal of Applied Physiology·Michael F FitzpatrickAlison M Girard
Sep 22, 2020·Brain Communications·Haralampos GouverisMuthuraman Muthuraman
Mar 5, 2016·Deutsches Ärzteblatt International·Ulrich J SommerBoris A Stuck
Mar 7, 2021·Facial Plastic Surgery : FPS·Samit N UnadkatHesham A Saleh
Sep 6, 2003·Otolaryngologic Clinics of North America·Wynne Chen, Clete A Kushida

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