Site-Selective γ-C(sp3 )-H and γ-C(sp2 )-H Arylation of Free Amino Esters Promoted by a Catalytic Transient Directing Group

Chemistry : a European Journal
Hua LinTheodore M Kamenecka

Abstract

The first selective PdII -catalysed γ-C(sp3 )-H and γ-C(sp2 )-H arylation of free amino esters using a commercially available catalytic transient directing group. A variety of free amino esters, including α-amino esters and β-amino esters, amino monoesters and amino bis-esters, are shown to react with a diverse range of simple aryl and heteroaryl iodide reagents.

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Citations

Jun 24, 2021·Journal of the American Chemical Society·Vinod G LandgeMichael C Young
Jul 2, 2021·The Journal of Organic Chemistry·Nurbey GuliaSławomir Szafert
May 5, 2020·Journal of the American Chemical Society·Yan-Qiao ChenJin-Quan Yu
Jul 22, 2021·Chemistry : a European Journal·Clément JacobGwilherm Evano
Apr 30, 2019·Journal of the American Chemical Society·Mohit KapoorMichael C Young

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