Site specific osteoarthritis and the index to ring finger length ratio

Osteoarthritis and Cartilage
B FerraroP E Leaverton

Abstract

To quantify the relationship between the index to ring finger length ratio second digit:fourth digit(2D:4D) and radiographic osteoarthritis (OA) of the knee. Data from the Clearwater Osteoarthritis Study (COS) were analyzed. We selected a random sample of 236 subjects with knee OA (Kellgren-Lawrence scores >or=2) and compared their finger length ratio pattern with a random sample of 242 controls. Finger length measurements were recorded from digitized hand radiographs. Subjects were classified into three groups: type 1 (index finger longer than ring finger), type 2 (fingers of equal length) and type 3 (index finger shorter than ring finger). Using a case-control design, we calculated odds ratios (OR). The type 3 finger pattern was significantly associated with knee OA (OR 2.59, 95% confidence interval (CI) 1.54-4.37). Women demonstrated a stronger association of visual type 3 finger pattern and knee OA (OR 4.40, 95% CI 2.62-7.38) compared to men (OR 2.59, 95% CI 1.34-5.00). The type 3 finger length pattern is associated, to a statistically significant degree, with OA of the knee. The type 3 finger length pattern (ring finger longer than index finger) appears to be an indicator of OA predisposition. Consideration of this pattern...Continue Reading

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Citations

Sep 29, 2011·Nature Reviews. Rheumatology·Andrew A Pitsillides, Frank Beier
Mar 17, 2015·Current Opinion in Rheumatology·Kelli D Allen, Yvonne M Golightly
Oct 24, 2017·Rheumatology International·L KalichmanE Kobyliansky
Jan 13, 2019·American Journal of Human Biology : the Official Journal of the Human Biology Council·Leonid KalichmanEugene Kobyliansky
Oct 1, 2019·American Journal of Human Biology : the Official Journal of the Human Biology Council·Leonid KalichmanEugene Kobyliansky
Aug 18, 2017·Medicine·Takuya YokoiHiroaki Nakamura

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