Situation specific effects of stressor controllability on plasma corticosterone changes in mice

Pharmacology, Biochemistry, and Behavior
C R Prince, H Anisman

Abstract

The immediate and proactive effects of controllable and uncontrollable stressors on plasma corticosterone were assessed in CD-1 mice. A progressive increase of plasma corticosterone concentrations was associated with graded increases in stressor severity. When a footshock stressor was employed, however, the magnitude of the glucocorticoid response, as well as the decay of plasma corticosterone concentrations, was independent of stressor controllability. This was the case regardless of the number of escapable vs. yoked inescapable shock trials mice received, the spacing of shock trials (i.e., applied within a single session or spaced over days), or the degree to which the escape response had been established. In contrast, in a swim task stressor controllability influenced plasma corticosterone concentrations provided that the escape response required of the animal was a highly prepared one (i.e., swim to an illuminated region). When mice were required to emit a contraprepared response (swim to dark) corticosterone concentrations did not differ between escapable and inescapable swim. It is suggested that glucocorticoid secretion is a fundamental response to stressors, and the differential effects of controllable and uncontrollabl...Continue Reading

References

Aug 1, 1979·Journal of Comparative and Physiological Psychology·H Anisman, L S Sklar
Jan 1, 1990·Pharmacology & Therapeutics·H Anisman, R M Zacharko
Jul 1, 1990·Pharmacology, Biochemistry, and Behavior·N ShanksH Anisman
Jan 1, 1988·Pharmacology, Biochemistry, and Behavior·B N BunnellG J Kant
Oct 1, 1986·Behavioral Neuroscience·S F MaierN H Kalin
Aug 1, 1986·Endocrine Reviews·R M SapolskyB S McEwen
Jan 1, 1987·Physiology & Behavior·B H NatelsonJ E Ottenweller
Jan 1, 1973·Journal of Comparative and Physiological Psychology·G D CooverS Levine
Oct 1, 1971·Journal of Comparative and Physiological Psychology·J M Weiss
Dec 1, 1984·Behavioral Neuroscience·T F HerrmannS Levine
Feb 1, 1984·Behavioral Neuroscience·A CorradiniH Anisman
Jan 1, 1982·Scandinavian Journal of Psychology·R C Murison, E Isaksen
Jun 1, 1981·Physiology & Behavior·B H NatelsonB E Levin
Jun 9, 1980·Brain Research·H AnismanL S Sklar

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Citations

Sep 4, 2007·Neuroscience and Behavioral Physiology·D F AvgustinovichL A Koryakina
Jun 1, 1993·Physiology & Behavior·L MenendezA Baamonde
Mar 14, 2002·Physiology & Behavior·Cristina OrsiniSimona Cabib
Sep 5, 2003·Physiology & Behavior·Francis X BrennanSteven F Maier
Mar 27, 2001·Pharmacology, Biochemistry, and Behavior·P L BrownR C Drugan
Jan 3, 2003·Psychoneuroendocrinology·S Retana-MárquezJ Velázquez-Moctezuma
Jan 1, 1997·Annual Review of Public Health·S KellyM Daniels
Sep 2, 1998·Proceedings of the National Academy of Sciences of the United States of America·C L ParksM Toth
May 29, 2014·Physiology & Behavior·John L ShannonhouseCaurnel Morgan
Jan 23, 2016·Frontiers in Behavioral Neuroscience·Osnat Hadad-OphirGal Richter-Levin
Jun 4, 2002·Nature Reviews. Neuroscience·Jeansok J Kim, David M Diamond
Feb 7, 2019·Behavioural Pharmacology·Simona CabibStefano Puglisi Allegra
Jan 18, 2006·Hippocampus·Christian Mirescu, Elizabeth Gould
Oct 14, 2019·Bulletin of Experimental Biology and Medicine·K A KasabovE A Anderzhanova
Mar 19, 2019·Frontiers in Behavioral Neuroscience·Catherine Jensen PeñaRosemary C Bagot

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