Six-minute walk test predicts all-cause mortality and technique failure in ambulatory peritoneal dialysis patients

Nephrology
Yuanyuan ShiWei Fang

Abstract

This study investigated the associated factors of 6-min walk test (6MWT) and its predictive value of outcome in patients undergoing peritoneal dialysis (PD). This is a single centre prospective observational cohort study. Stable ambulatory PD patients in our centre between 1 May 2010 and 30 April 2011 were enrolled in this study. All included subjects performed 6MWT, and 6-min walk distances (6MWDs) were recorded. Patients were divided into two groups according to 6MWD and prospectively followed up until death, cessation of PD or to the end of the study (30 September 2012). A total of 145 patients were enrolled, including 63 (43%) males. Multiple stepwise regression showed that age (β = -0.295, P = 0.001), diastolic blood pressure (DBP) (β = 0.292, P = 0.001), left ventricular ejection fraction (LVEF) (β = 0.198, P = 0.019) were independently associated with lower 6MWD. By the end of the study, six (8%) patients died in long 6MWD group while 15 (20%) died in the short 6MWD group, a significantly lower patient survival was observed in short 6MWD group (Log-rank = 4.983, P = 0.026). Patients with short 6MWD also showed inferior technique survival (Log-rank = 4.838, P = 0.028). There was no significant difference in peritonitis-fr...Continue Reading

References

Mar 8, 1986·British Medical Journal·D P LipkinP A Poole-Wilson
Jan 1, 1996·Annals of Internal Medicine·P O LimT M MacDonald
May 7, 1999·Advances in Renal Replacement Therapy·K L Johansen
Nov 30, 1999·Experimental Aging Research·R J Shephard
Aug 31, 2000·The New England Journal of Medicine·N L Jones, K J Killian
Dec 1, 2001·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·A LevinC Thompson
Jan 5, 2002·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Kathy E SietsemaEric P Brass
Jul 2, 2002·American Journal of Respiratory and Critical Care Medicine·UNKNOWN ATS Committee on Proficiency Standards for Clinical Pulmonary Function Laboratories
May 19, 2005·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Alexander S Goldfarb-RumyantzevAlfred K Cheung
Sep 30, 2005·Hemodialysis International·Patricia Painter
Sep 16, 2008·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Wei FangDimitrios G Oreopoulos
Oct 31, 2008·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Toshihiko IshimitsuHiroaki Matsuoka
Jan 8, 2011·Clinical Journal of the American Society of Nephrology : CJASN·Angela Yee-Moon WangJohn E Sanderson
Mar 2, 2011·Physiotherapy Canada. Physiothérapie Canada·Tom OverendHeather Locking-Cusolito
Mar 25, 2011·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Shuchi AnandManjula Kurella Tamura
Apr 30, 2011·Clinical Journal of the American Society of Nephrology : CJASN·Usama FerozeKamyar Kalantar-Zadeh
Sep 4, 2012·Peritoneal Dialysis International : Journal of the International Society for Peritoneal Dialysis·Giuseppe EniaCarmine Zoccali
Sep 4, 2014·Peritoneal Dialysis International : Journal of the International Society for Peritoneal Dialysis·Qingdong XuHaiping Mao

❮ Previous
Next ❯

Citations

Nov 11, 2017·Peritoneal Dialysis International : Journal of the International Society for Peritoneal Dialysis·Sharlene Greenwood
Nov 28, 2018·Peritoneal Dialysis International : Journal of the International Society for Peritoneal Dialysis·Kiyotaka UchiyamaHiroshi Itoh
Nov 29, 2020·Clinical Transplantation·Daniel J WatfordJane C Tan
Jun 9, 2020·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Xingxing S ChengJane C Tan
Mar 10, 2021·Aging Clinical and Experimental Research·Jonathan MyersRalph Rabkin

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.