Six weeks of high-intensity interval training to exhaustion attenuates dynamic cerebral autoregulation without influencing resting cerebral blood velocity in young fit men

Physiological Reports
Audrey DrapeauPatrice Brassard

Abstract

Elevated cardiorespiratory fitness (CRF) is associated with reduced dynamic cerebral autoregulation (dCA), but the impact of exercise training per se on dCA remains equivocal. In addition, resting cerebral blood flow (CBF) and dCA after high-intensity interval training (HIIT) in individuals with already high CRF remains unknown. We examined to what extent 6 weeks of HIIT affect resting CBF and dCA in cardiorespiratory fit men and explored if potential changes are intensity-dependent. Endurance-trained men were assigned to group HIIT85 (85% of maximal aerobic power, 1-7 min effort bouts, n = 8) and HIIT115 (115% of maximal aerobic power, 30 sec to 1 min effort bouts, n = 9). Training sessions were completed until exhaustion 3 times/week over 6 weeks. Mean arterial pressure (MAP) and middle cerebral artery mean blood velocity (MCAvmean ) were measured continuously at rest and during repeated squat-stands (0.05 and 0.10 Hz). Transfer function analysis (TFA) was used to characterize dCA on driven blood pressure oscillations during repeated squat-stands. Neither training nor intensity had an effect on resting MAP and MCAvmean (both P > 0.05). TFA phase during 0.10 Hz squat-stands decreased after HIIT irrespective of intensity (HIIT8...Continue Reading

References

Jan 1, 1989·Stroke; a Journal of Cerebral Circulation·R AaslidH Nornes
Feb 12, 1998·The American Journal of Physiology·R ZhangB D Levine
Jul 8, 2000·Stroke; a Journal of Cerebral Circulation·J M SerradorR L Bondar
Mar 20, 2008·Clinical Science·Yu-Sok KimJohannes J van Lieshout
Jul 19, 2008·The Journal of Physiology·Philip N AinslieGreg Atkinson
Feb 13, 2009·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Philip N Ainslie, James Duffin
Mar 5, 2011·Journal of Applied Physiology·Mikkel Lind-HolstFrank C Pott
Jun 4, 2011·Stroke; a Journal of Cerebral Circulation·Frederick M IveyRichard F Macko
Nov 10, 2012·Journal of Applied Physiology·Vincent L AengevaerenRong Zhang
Mar 26, 2013·Journal of Magnetic Resonance Imaging : JMRI·Binu P ThomasHanzhang Lu
May 15, 2013·Scandinavian Journal of Medicine & Science in Sports·D IchikawaS Ogoh
Aug 22, 2013·Stroke; a Journal of Cerebral Circulation·Damian M BaileyPhilip N Ainslie
Jan 8, 2014·The Journal of Physiology·Christopher K WilliePhilip N Ainslie
Sep 27, 2014·Journal of Applied Physiology·Philip N Ainslie, Ryan L Hoiland
Oct 2, 2014·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Julien V BrugniauxDamian M Bailey
Apr 3, 2015·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Samuel J E LucasDamian M Bailey
Jan 20, 2016·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Jurgen A H R ClaassenUNKNOWN international Cerebral Autoregulation Research Network (CARNet)
Feb 19, 2016·Scandinavian Journal of Medicine & Science in Sports·M PaquetteP Brassard
Mar 20, 2016·Scandinavian Journal of Medicine & Science in Sports·I D BrazJ P Fisher
Oct 18, 2016·The Journal of Physiology·Martin J MacInnis, Martin J Gibala
Aug 9, 2017·Experimental Physiology·Kurt J Smith, Philip N Ainslie
Oct 14, 2017·Journal of the American Heart Association·Simon MalenfantSteeve Provencher
Nov 17, 2017·Journal of Neurotrauma·Aaron A PhillipsAndrei V Krassioukov
Oct 27, 2018·American Journal of Physiology. Heart and Circulatory Physiology·Nia LewisNeil D Eves
Dec 18, 2018·Journal of Science and Medicine in Sport·Joseph M NortheyBen Rattray
Jan 15, 2019·Journal of Alzheimer's Disease : JAD·Alfonso J AlfiniJ Carson Smith
Jan 18, 2019·Physiological Reports·Lawrence LabrecquePatrice Brassard
Feb 2, 2019·American Journal of Physiology. Heart and Circulatory Physiology·Michelle E Favre, Jorge M Serrador

❮ Previous
Next ❯

Citations

Apr 30, 2020·The Journal of Physiology·Thomas A CalverleyDamian M Bailey
Jan 16, 2021·American Journal of Physiology. Heart and Circulatory Physiology·Jennifer S WilliamsMaureen J MacDonald
Mar 12, 2021·Journal of Applied Physiology·Mohammed R AlwatbanSandra A Billinger
Mar 27, 2021·Physiological Reviews·Jurgen A H R ClaassenFrank M Faraci

❮ Previous
Next ❯

Software Mentioned

Ensemble
GraphPad
LabChart
Prism for macOS

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.