Six-Year Incidence and Baseline Risk Factors for Pseudoexfoliation in a South Indian Population: The Chennai Eye Disease Incidence Study

Ophthalmology
Lingam VijayaRonnie George

Abstract

To estimate the 6-year incidence of pseudoexfoliation and its risk factors in a South Indian population. Longitudinal population-based study. Subjects 40 years of age or older without pseudoexfoliation at baseline. Participants were examined at baseline and after a 6-year interval. The presence of pseudoexfoliation was looked for after pupillary dilation in either or both eyes at 1 or more locations. Glaucoma was defined using the International Society of Geographical and Epidemiological Ophthalmology Classification. Logistic regression was performed to identify the baseline risk factors that could predict the incident pseudoexfoliation. Six-year incidence, associated risk factors, and rural-versus-urban differences. From the study cohort of 4228 subjects, 87 subjects (male-to-female ratio, 48:39; rural-to-urban ratio, 69:18) demonstrated incident pseudoexfoliation (2.03%; 95% confidence interval [CI], 1.6-2.5; rural: -2.86%; 95% CI, 1.6-2.5; urban: 0.96%; 95% CI, 0.5-1.4). Pseudoexfoliation was associated with glaucoma in 1 subject (1.1%), with primary angle-closure suspicion in 10 subjects (11.5%), and with ocular hypertension in 2 subjects (2.2%). Significant predictive baseline risk factors were older age (P < 0.001), rural...Continue Reading

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Feb 9, 2018·Journal of Glaucoma·Anastasios G P Konstas, Amund Ringvold
Oct 2, 2019·Acta Ophthalmologica·Curt Ekström, Lovisa Winblad von Walter
Jan 7, 2020·Oman Journal of Ophthalmology·Thanigasalam Thevi, Adinegara Lutfi Abas
Jun 16, 2021·Journal of Glaucoma·Panayiota FountiFotis Topouzis
Nov 21, 2021·International Ophthalmology·Adi Mohammed Al OwaifeerDeepak P Edward

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